| November 16, 2025 | @ Brigham Young Cougars | L 60-83 | 0-1 | C. James 14 | D. Bibby 3 | J. Palmer 9 |
| November 23, 2025 | MANHATTAN JASPERS | L 55-76 | 0-2 | D. Bibby 12 | L. Angner 3 | J. Palmer 10 |
| November 26, 2025 | WICHITA STATE SHOCKERS | W 69-65 OT | 1-2 | C. James 15 | B. Davis 3 | C. James 11 |
| November 30, 2025 | MARIST RED FOXES | W 76-71 | 2-2 | A. Xavier 14 | D. Bibby 3 | A. Xavier 6 |
| December 3, 2025 | AUSTIN PEAY GOVERNORS | W 76-67 | 3-2 | C. James 17 | C. James 3 | J. Palmer 6 |
| December 7, 2025 | COASTAL CAROLINA CHANTICLEERS | L 58-66 | 3-3 | C. James 12 | J. Palmer 5 | J. Palmer 6 |
| December 13, 2025 | #9 MISSOURI TIGERS | L 72-78 | 3-4 | D. Bibby 19 | A. Xavier 6 | D. Bibby 5 |
| December 20, 2025 | GARDNER-WEBB RUNNIN' BULLDOGS | W 77-62 | 4-4 | C. James 29 | D. Bibby 3 | B. Jackson 6 |
| December 23, 2025 | CENTRAL FLORIDA KNIGHTS Empire Classic | L 59-76 | 4-5 | D. Bibby 14 | J. Palmer 3 | J. Palmer 8 |
| December 26, 2025 | @ UCLA Bruins (9-2, 0-0, 6-1 Home)* | - | | | | |
| December 28, 2025 | OREGON DUCKS (7-2, 0-0, 0-1 Away)* | - | | | | |
| January 2, 2026 | @ Iowa Hawkeyes (3-6, 0-0, 3-4 Home)* | - | | | | |
| January 4, 2026 | @ Michigan State Spartans (8-3, 0-0, 6-0 Home)* | - | | | | |
| January 9, 2026 | @ Ohio State Buckeyes (6-3, 0-0, 6-2 Home)* | - | | | | |
| January 11, 2026 | @ Southern California Trojans (9-1, 0-0, 8-0 Home)* | - | | | | |
| January 16, 2026 | WASHINGTON HUSKIES (7-4, 0-0, 1-0 Away)* | - | | | | |
| January 18, 2026 | @ Purdue Boilermakers (7-3, 0-0, 5-1 Home)* | - | | | | |
| January 23, 2026 | @ Minnesota Golden Gophers (7-2, 0-0, 6-0 Home)* | - | | | | |
| January 25, 2026 | WISCONSIN BADGERS (8-1, 0-0, 1-1 Away)* | - | | | | |
| January 30, 2026 | NORTHWESTERN WILDCATS (6-3, 0-0, 0-2 Away)* | - | | | | |
| February 1, 2026 | NEBRASKA CORNHUSKERS (6-3, 0-0, 1-2 Away)* | - | | | | |
| February 6, 2026 | @ Rutgers Scarlet Knights (5-4, 0-0, 5-2 Home)* | - | | | | |
| February 8, 2026 | MICHIGAN WOLVERINES (5-4, 0-0, 0-0 Away)* | - | | | | |
| February 13, 2026 | INDIANA HOOSIERS (5-5, 0-0, 0-2 Away)* | - | | | | |
| February 15, 2026 | @ Maryland Terrapins (4-5, 0-0, 4-2 Home)* | - | | | | |
| February 20, 2026 | PENN STATE NITTANY LIONS (8-3, 0-0, 0-2 Away)* | - | | | | |
| February 22, 2026 | @ Penn State Nittany Lions (8-3, 0-0, 6-0 Home)* | - | | | | |
| February 27, 2026 | MICHIGAN STATE SPARTANS (8-3, 0-0, 0-2 Away)* | - | | | | |
| March 1, 2026 | IOWA HAWKEYES (3-6, 0-0, 0-1 Away)* | - | | | | |
