| November 25, 2027 | #8 PITTSBURGH PANTHERS | W 96-93 | 1-0 | K. Shannon 21 | K. Shannon 9 | D. Bibby 12 |
| November 27, 2027 | OHIO STATE BUCKEYES | W 86-64 | 2-0 | K. Shannon 17 | K. Shannon 7 | D. McQuay 5 |
| November 30, 2027 | JACKSONVILLE STATE GAMECOCKS | W 75-72 | 3-0 | E. Tenys 16 | K. Shannon 6 | D. Bibby 11 |
| December 6, 2027 | NORTHWESTERN WILDCATS | W 69-48 | 4-0 | K. Shannon 16 | E. Tenys 3 | D. Lofton 13 |
| December 9, 2027 | MASSACHUSETTS MINUTEMEN Jimmy V Classic | W 77-74 | 5-0 | D. Lofton 19 | K. Shannon 4 | D. Lofton 18 |
| December 10, 2027 | FLORIDA STATE SEMINOLES Jimmy V Classic | L 72-79 | 5-1 | K. Shannon 16 | K. Shannon 7 | R. Brooks 5 |
| December 13, 2027 | @ Rice Owls | W 105-75 | 6-1 | D. Lofton 21 | K. Shannon 10 | D. Bibby 10 |
| December 17, 2027 | EASTERN WASHINGTON EAGLES | W 79-57 | 7-1 | K. Shannon 17 | K. Shannon 8 | D. Lofton 14 |
| December 20, 2027 | SOUTH DAKOTA COYOTES | W 71-60 | 8-1 | R. Brooks 18 | R. Brooks 7 | D. Lofton 11 |
| December 23, 2027 | #23 MARYLAND TERRAPINS | L 65-71 | 8-2 | D. Lofton 15 | K. Shannon 5 | D. Bibby 13 |
| December 28, 2027 | #13 OKLAHOMA STATE COWBOYS* | W 83-67 | 9-2 | E. Tenys 21 | K. Shannon 4 | D. Bibby 10 |
| December 30, 2027 | @ #1 Kansas Jayhawks* | L 68-72 | 9-3 | E. Tenys 13 | K. Shannon 6 | D. Bibby 6 |
| January 4, 2028 | CENTRAL FLORIDA KNIGHTS* | W 82-70 | 10-3 | D. Lofton 18 | K. Shannon 5 | D. Lofton 11 |
| January 6, 2028 | @ Iowa State Cyclones* | W 88-83 | 11-3 | D. Lofton 26 | K. Shannon 5 | D. Lofton 11 |
| January 9, 2028 | UTAH UTES* | W 97-93 | 12-3 | R. Brooks 17 | K. Shannon 5 | L. Bayno 7 |
| January 13, 2028 | @ Texas Christian Horned Frogs* | W 76-70 | 13-3 | R. Brooks 21 | K. Shannon 4 | D. Lofton 15 |
| January 18, 2028 | @ Colorado Buffaloes* | L 76-79 | 13-4 | D. Lofton 23 | R. Brooks 5 | D. Lofton 12 |
| January 20, 2028 | TEXAS TECH RED RAIDERS* | L 74-83 | 13-5 | D. Lofton 12 | K. Shannon 3 | D. Lofton 9 |
| January 25, 2028 | BAYLOR BEARS* | W 82-69 | 14-5 | K. Shannon 20 | K. Shannon 5 | D. Lofton 15 |
| January 27, 2028 | @ #7 Arizona Wildcats* | L 72-74 | 14-6 | K. Shannon 18 | K. Shannon 3 | R. Brooks 9 |
| February 1, 2028 | #10 CINCINNATI BEARCATS* | W 86-75 | 15-6 | D. Lofton 20 | B. Rogers 4 | D. Lofton 15 |
| February 3, 2028 | @ Texas Tech Red Raiders* | L 64-67 | 15-7 | E. Tenys 15 | K. Shannon 6 | D. Bibby 11 |
| February 8, 2028 | @ #3 West Virginia Mountaineers* | L 69-96 | 15-8 | K. Shannon 13 | K. Shannon 7 | L. Bayno 7 |
| February 10, 2028 | #19 BRIGHAM YOUNG COUGARS* | W 76-69 | 16-8 | K. Shannon 24 | R. Brooks 6 | D. Lofton 13 |
| February 15, 2028 | ARIZONA STATE SUN DEVILS* | L 76-83 | 16-9 | K. Shannon 21 | B. Rogers 4 | D. Bibby 7 |
| February 17, 2028 | @ #13 Cincinnati Bearcats* | L 73-75 | 16-10 | D. Bibby 15 | R. Brooks 3 | D. Lofton 10 |
| February 22, 2028 | @ #25 Oklahoma State Cowboys* | L 72-98 | 16-11 | K. Shannon 21 | K. Shannon 3 | D. Bibby 7 |
| February 24, 2028 | #2 WEST VIRGINIA MOUNTAINEERS* | L 70-91 | 16-12 | K. Shannon 19 | D. Bibby 5 | D. Bibby 6 |
| March 1, 2028 | @ Kansas State Wildcats* | W 71-69 | 17-12 | D. Bibby 22 | K. Shannon 8 | L. Bayno 7 |
| March 3, 2028 | TEXAS CHRISTIAN HORNED FROGS* | W 102-78 | 18-12 | R. Brooks 17 | K. Shannon 8 | D. Lofton 13 |
| March 9, 2028 | IOWA STATE CYCLONES Big 12 Tournament | W 84-69 | 19-12 | D. Lofton 32 | K. Shannon 8 | D. Lofton 16 |
| March 10, 2028 | @ #2 West Virginia Mountaineers Big 12 Tournament | L 77-85 | 19-13 | K. Shannon 26 | K. Shannon 4 | R. Brooks 7 |
