| November 16, 2027 | @ Syracuse Orange | L 50-77 | 0-1 | A. Boulware 9 | J. Redd 3 | S. Sheppard 7 |
| November 19, 2027 | MORGAN STATE BEARS | W 77-73 | 1-1 | J. Redd 17 | J. Redd 5 | S. Sheppard 9 |
| November 23, 2027 | @ Georgia Bulldogs | L 60-76 | 1-2 | C. Hammond 11 | W. Robertson 5 | A. Boulware 10 |
| November 26, 2027 | HAWAII RAINBOW WARRIORS | L 82-89 OT | 1-3 | S. Sheppard 23 | J. Redd 8 | S. Sheppard 16 |
| November 30, 2027 | @ Virginia Tech Hokies | L 68-82 | 1-4 | S. Sheppard 10 | S. Bree 5 | S. Sheppard 9 |
| December 7, 2027 | NEW MEXICO STATE AGGIES | L 67-73 | 1-5 | W. Robertson 17 | W. Robertson 4 | A. Boulware 10 |
| December 9, 2027 | WESTERN CAROLINA CATAMOUNTS Nassau Championship | W 92-85 | 2-5 | J. Redd 21 | J. Redd 6 | D. Powers 9 |
| December 10, 2027 | @ Miami (FL) Hurricanes Nassau Championship | L 66-69 | 2-6 | D. Powers 21 | J. Redd 6 | W. Robertson 6 |
| December 14, 2027 | @ Grand Canyon Antelopes | L 67-84 | 2-7 | W. Robertson 22 | J. Redd 7 | A. Boulware 8 |
| December 21, 2027 | NEW MEXICO LOBOS | W 82-65 | 3-7 | S. Sheppard 18 | J. Redd 5 | A. Boulware 11 |
| December 26, 2027 | XAVIER MUSKETEERS* | W 77-75 | 4-7 | A. Boulware 21 | J. Redd 4 | S. Sheppard 10 |
| December 30, 2027 | @ St. Johns Red Storm* | L 55-75 | 4-8 | D. Powers 11 | J. Redd 4 | S. Sheppard 6 |
| January 2, 2028 | BUTLER BULLDOGS* | W 70-46 | 5-8 | A. Boulware 13 | J. Redd 4 | A. Boulware 6 |
| January 4, 2028 | DEPAUL BLUE DEMONS* | W 80-50 | 6-8 | D. Powers 13 | J. Redd 8 | S. Sheppard 8 |
| January 6, 2028 | @ #25 Marquette Golden Eagles* | L 61-73 | 6-9 | A. Boulware 11 | J. Redd 4 | A. Boulware 7 |
| January 11, 2028 | #12 CREIGHTON BLUE JAYS* | L 63-74 | 6-10 | W. Robertson 13 | J. Redd 5 | S. Sheppard 8 |
| January 13, 2028 | @ Providence Friars* | L 59-75 | 6-11 | D. Powers 11 | J. Redd 7 | W. Robertson 5 |
| January 18, 2028 | GEORGETOWN HOYAS* | W 71-54 | 7-11 | S. Sheppard 21 | J. Redd 7 | S. Sheppard 12 |
| January 20, 2028 | VILLANOVA WILDCATS* | L 47-55 | 7-12 | S. Sheppard 16 | W. Robertson 3 | S. Sheppard 7 |
| January 25, 2028 | @ #11 Connecticut Huskies* | L 61-74 | 7-13 | A. Boulware 18 | W. Robertson 6 | S. Sheppard 8 |
| January 27, 2028 | @ DePaul Blue Demons* | W 70-59 | 8-13 | W. Robertson 17 | J. Redd 6 | D. Powers 8 |
| February 1, 2028 | MARQUETTE GOLDEN EAGLES* | L 66-85 | 8-14 | A. Boulware 19 | B. Sura 5 | A. Boulware 6 |
| February 3, 2028 | ST. JOHNS RED STORM* | W 85-62 | 9-14 | J. Redd 13 | J. Redd 6 | S. Sheppard 9 |
| February 8, 2028 | @ Villanova Wildcats* | L 64-67 | 9-15 | J. Redd 16 | J. Redd 4 | A. Boulware 10 |
| February 10, 2028 | @ Georgetown Hoyas* | L 73-76 | 9-16 | A. Boulware 14 | J. Redd 5 | A. Boulware 12 |
| February 17, 2028 | #7 CONNECTICUT HUSKIES* | W 83-82 | 10-16 | C. Hammond 24 | W. Robertson 5 | S. Sheppard 9 |
| February 22, 2028 | PROVIDENCE FRIARS* | L 57-64 | 10-17 | W. Robertson 18 | J. Redd 5 | S. Sheppard 9 |
| February 27, 2028 | @ #14 Creighton Blue Jays* | L 91-93 OT | 10-18 | J. Redd 20 | J. Redd 9 | S. Sheppard 14 |
| March 1, 2028 | @ Xavier Musketeers* | L 64-65 | 10-19 | S. Sheppard 17 | J. Redd 5 | S. Sheppard 8 |
| March 3, 2028 | @ Butler Bulldogs* | W 80-73 OT | 11-19 | A. Boulware 19 | D. Powers 4 | S. Sheppard 10 |
| March 9, 2028 | ST. JOHNS RED STORM (14-17, 1-10 Away) Big East Tournament | - | | | | |
