| November 16, 2027 | MISSISSIPPI VALLEY DELTA DEVILS | W 58-38 | 1-0 | W. West 10 | S. Smith 2 | C. Carter 8 |
| November 19, 2027 | COLUMBIA LIONS | W 87-61 | 2-0 | W. West 22 | C. Carter 6 | C. Carter 9 |
| November 23, 2027 | SOUTH ALABAMA JAGUARS | W 96-83 | 3-0 | C. Frahm 20 | S. Smith 5 | C. Frahm 6 |
| November 26, 2027 | @ UCLA Bruins | L 69-87 | 3-1 | S. Smith 18 | C. Carter 4 | R. Rayner 10 |
| November 30, 2027 | #25 MARYLAND TERRAPINS | W 84-74 | 4-1 | B. Jones 15 | S. Smith 4 | C. Carter 9 |
| December 7, 2027 | NICHOLLS STATE COLONELS | W 96-70 | 5-1 | C. Carter 14 | W. West 5 | R. Rayner 7 |
| December 14, 2027 | JAMES MADISON DUKES | W 78-62 | 6-1 | W. West 23 | C. Carter 5 | C. Carter 9 |
| December 21, 2027 | @ Seattle Redhawks | W 86-82 | 7-1 | W. West 25 | W. West 4 | C. Carter 11 |
| December 23, 2027 | @ Louisiana State Fighting Tigers Gulf Coast Showcase | L 77-87 | 7-2 | A. Forbes 17 | S. Smith 3 | B. Jones 11 |
| December 26, 2027 | @ Syracuse Orange* | L 65-82 | 7-3 | W. West 18 | S. Smith 4 | W. West 5 |
| December 28, 2027 | FLORIDA STATE SEMINOLES* | W 85-74 | 8-3 | W. West 36 | S. Smith 8 | B. Jones 12 |
| January 2, 2028 | @ Wake Forest Demon Deacons* | L 78-88 | 8-4 | W. West 14 | S. Smith 2 | B. Jones 8 |
| January 4, 2028 | MIAMI (FL) HURRICANES* | L 69-76 | 8-5 | W. West 19 | C. Carter 4 | W. West 6 |
| January 9, 2028 | @ #1 Duke Blue Devils* | L 58-82 | 8-6 | W. West 19 | S. Smith 3 | R. Rayner 8 |
| January 11, 2028 | #10 VIRGINIA CAVALIERS* | L 62-89 | 8-7 | R. Rayner 15 | C. Carter 6 | C. Carter 8 |
| January 16, 2028 | NORTH CAROLINA TAR HEELS* | L 65-79 | 8-8 | J. Henderson 16 | S. Smith 5 | C. Carter 11 |
| January 18, 2028 | CALIFORNIA GOLDEN BEARS* | L 65-80 | 8-9 | W. West 14 | S. Smith 4 | C. Carter 6 |
| January 23, 2028 | @ Stanford Cardinal* | L 75-92 | 8-10 | W. West 17 | S. Smith 6 | W. West 5 |
| January 25, 2028 | VIRGINIA TECH HOKIES* | W 73-64 | 9-10 | B. Jones 11 | S. Smith 5 | V. Allen 10 |
| January 30, 2028 | @ NC-State Wolfpack* | L 58-75 | 9-11 | S. Smith 16 | S. Smith 6 | B. Jones 9 |
| February 1, 2028 | @ Southern Methodist Mustangs* | L 66-81 | 9-12 | C. Carter 16 | S. Smith 4 | R. Rayner 8 |
| February 6, 2028 | @ Clemson Tigers* | L 62-82 | 9-13 | W. West 21 | C. Carter 3 | W. West 5 |
| February 8, 2028 | @ Notre Dame Fighting Irish* | L 72-76 | 9-14 | R. Rayner 17 | W. West 6 | B. Jones 10 |
| February 13, 2028 | PITTSBURGH PANTHERS* | W 78-69 | 10-14 | E. Carey 19 | S. Smith 6 | R. Rayner 9 |
| February 15, 2028 | BOSTON COLLEGE EAGLES* | L 78-89 | 10-15 | W. West 12 | S. Smith 4 | C. Carter 9 |
| February 20, 2028 | #8 LOUISVILLE CARDINALS* | L 87-101 OT | 10-16 | R. Rayner 22 | C. Carter 6 | C. Carter 11 |
| February 22, 2028 | @ #25 North Carolina Tar Heels* | L 83-99 | 10-17 | B. Jones 15 | S. Smith 4 | C. Carter 9 |
| February 27, 2028 | #19 SYRACUSE ORANGE* | L 69-74 | 10-18 | W. West 23 | S. Smith 4 | C. Carter 5 |
| March 1, 2028 | @ Pittsburgh Panthers* | L 73-80 | 10-19 | C. Frahm 11 | C. Carter 5 | B. Jones 12 |
