| November 16, 2025 | LOUISIANA STATE FIGHTING TIGERS | L 68-72 | 0-1 | C. Spatola 21 | C. Spatola 7 | C. Fuller 13 |
| November 18, 2025 | AUSTIN PEAY GOVERNORS Sunshine Slam | L 78-79 | 0-2 | C. Fuller 18 | C. Spatola 5 | C. Fuller 9 |
| November 23, 2025 | SACRAMENTO STATE HORNETS | L 61-69 | 0-3 | J. Edwards 15 | C. Spatola 6 | M. Ray 6 |
| November 26, 2025 | WILLIAM & MARY TRIBE | W 67-66 | 1-3 | O. Oliver 29 | C. Spatola 6 | M. Ray 8 |
| November 30, 2025 | @ #11 West Virginia Mountaineers | L 57-72 | 1-4 | C. Fuller 22 | C. Spatola 4 | C. Fuller 11 |
| December 3, 2025 | @ Oregon Ducks | L 65-83 | 1-5 | C. Fuller 25 | C. Spatola 2 | C. Fuller 19 |
| December 7, 2025 | @ Washington State Cougars | L 65-86 | 1-6 | C. Spatola 13 | C. Spatola 4 | C. Fuller 6 |
| December 13, 2025 | @ Syracuse Orange | L 57-75 | 1-7 | O. Oliver 11 | J. Edwards 3 | C. Fuller 6 |
| December 21, 2025 | @ New Mexico Lobos | W 79-78 | 2-7 | C. Fuller 19 | C. Spatola 8 | C. Fuller 7 |
| December 26, 2025 | @ Seton Hall Pirates* | L 65-68 | 2-8 | C. Spatola 11 | C. Spatola 5 | J. Edwards 6 |
| December 30, 2025 | XAVIER MUSKETEERS* | W 72-55 | 3-8 | C. Spatola 20 | J. Edwards 4 | C. Fuller 8 |
| January 2, 2026 | @ #24 Villanova Wildcats* | L 58-80 | 3-9 | C. Spatola 14 | J. Edwards 4 | C. Fuller 8 |
| January 4, 2026 | ST. JOHNS RED STORM* | L 65-72 | 3-10 | C. Fuller 16 | J. Edwards 4 | C. Fuller 6 |
| January 11, 2026 | @ #23 Providence Friars* | L 66-76 | 3-11 | C. Fuller 16 | C. Spatola 4 | C. Fuller 9 |
| January 13, 2026 | @ Butler Bulldogs* | L 67-84 | 3-12 | C. Fuller 20 | C. Fuller 3 | C. Fuller 5 |
| January 20, 2026 | DEPAUL BLUE DEMONS* | L 85-88 OT | 3-13 | C. Fuller 20 | C. Spatola 6 | C. Fuller 9 |
| January 23, 2026 | CREIGHTON BLUE JAYS* | L 71-85 | 3-14 | C. Spatola 17 | C. Spatola 5 | M. Ray 6 |
| January 27, 2026 | @ Marquette Golden Eagles* | L 59-73 | 3-15 | J. Edwards 13 | C. Spatola 10 | O. Oliver 8 |
| January 30, 2026 | @ #5 Connecticut Huskies* | L 64-82 | 3-16 | C. Fuller 14 | C. Spatola 6 | C. Fuller 7 |
| February 1, 2026 | @ St. Johns Red Storm* | L 59-65 | 3-17 | C. Fuller 19 | C. Spatola 9 | C. Fuller 10 |
| February 3, 2026 | BUTLER BULLDOGS* | L 66-76 | 3-18 | C. Fuller 22 | C. Spatola 5 | C. Fuller 8 |
| February 8, 2026 | #20 PROVIDENCE FRIARS* | W 52-39 | 4-18 | J. Edwards 12 | C. Fuller 4 | C. Fuller 12 |
| February 10, 2026 | @ Xavier Musketeers* | L 65-77 | 4-19 | C. Fuller 16 | J. Edwards 5 | C. Fuller 12 |
| February 15, 2026 | MARQUETTE GOLDEN EAGLES* | W 81-68 | 5-19 | C. Spatola 18 | J. Edwards 4 | C. Fuller 8 |
| February 17, 2026 | #4 CONNECTICUT HUSKIES* | L 64-75 | 5-20 | J. Edwards 21 | C. Spatola 4 | C. Fuller 10 |
| February 22, 2026 | @ DePaul Blue Demons* | W 80-63 | 6-20 | C. Fuller 20 | C. Spatola 5 | C. Fuller 11 |
| February 24, 2026 | @ Creighton Blue Jays* | L 53-69 | 6-21 | C. Fuller 13 | C. Spatola 5 | C. Fuller 12 |
| March 1, 2026 | SETON HALL PIRATES* | L 85-88 OT | 6-22 | J. Edwards 26 | C. Spatola 6 | C. Fuller 8 |
| March 3, 2026 | #25 VILLANOVA WILDCATS* | L 67-84 | 6-23 | C. Fuller 16 | C. Spatola 3 | C. Spatola 5 |
| March 9, 2026 | @ Providence Friars Big East Tournament | L 73-85 | 6-24 | J. Edwards 12 | J. Edwards 6 | J. Edwards 7 |
