| November 16, 2027 | VMI KEYDETS | W 62-43 | 1-0 | D. Quigley 17 | J. Lockwood 2 | A. Peskine 7 |
| November 19, 2027 | LEHIGH MOUNTAIN HAWKS | L 58-69 | 1-1 | A. Peskine 11 | J. Lockwood 4 | A. Peskine 15 |
| November 23, 2027 | PRINCETON TIGERS | W 80-77 | 2-1 | A. Peskine 17 | J. Chatman 5 | A. Peskine 12 |
| November 26, 2027 | ARKANSAS STATE RED WOLVES | W 96-82 | 3-1 | J. Chatman 18 | J. Lockwood 8 | B. Weaver 6 |
| November 30, 2027 | UC-SANTA BARBARA GAUCHOS | W 82-69 | 4-1 | A. Peskine 19 | Q. Hinder 6 | A. Peskine 9 |
| December 7, 2027 | SOUTH DAKOTA STATE JACKRABBITS | W 100-65 | 5-1 | Q. Hinder 19 | J. Lockwood 6 | B. Weaver 8 |
| December 13, 2027 | #4 FLORIDA GATORS | W 89-80 | 6-1 | J. Chatman 26 | Q. Hinder 7 | B. Weaver 12 |
| December 16, 2027 | FLORIDA GULF COAST EAGLES Battle 4 Atlantis | L 91-98 | 6-2 | D. Quigley 18 | J. Lockwood 7 | A. Peskine 9 |
| December 21, 2027 | WILLIAM & MARY TRIBE | W 93-71 | 7-2 | J. Lockwood 17 | J. Lockwood 7 | C. Edwards 7 |
| December 26, 2027 | SOUTHERN METHODIST MUSTANGS* | L 76-79 | 7-3 | J. Chatman 18 | J. Lockwood 7 | T. Anthony 9 |
| December 28, 2027 | @ Georgia Tech Yellow Jackets* | L 74-85 | 7-4 | J. Lockwood 17 | J. Lockwood 4 | A. Peskine 14 |
| January 2, 2028 | @ Stanford Cardinal* | W 75-74 | 8-4 | C. Edwards 17 | J. Lockwood 5 | A. Peskine 13 |
| January 4, 2028 | NOTRE DAME FIGHTING IRISH* | L 72-74 | 8-5 | J. Chatman 21 | Q. Hinder 4 | D. Quigley 6 |
| January 9, 2028 | CLEMSON TIGERS* | W 80-74 OT | 9-5 | A. Peskine 18 | J. Lockwood 7 | A. Peskine 8 |
| January 11, 2028 | PITTSBURGH PANTHERS* | L 79-92 | 9-6 | D. Quigley 15 | A. Peskine 6 | A. Peskine 9 |
| January 16, 2028 | #22 SYRACUSE ORANGE* | L 86-88 | 9-7 | J. Chatman 17 | J. Chatman 6 | A. Peskine 9 |
| January 18, 2028 | @ Miami (FL) Hurricanes* | L 74-79 | 9-8 | J. Chatman 22 | B. Weaver 3 | B. Weaver 6 |
| January 23, 2028 | #25 NORTH CAROLINA TAR HEELS* | L 86-89 | 9-9 | A. Peskine 26 | J. Chatman 8 | A. Peskine 14 |
| January 25, 2028 | @ #6 Virginia Cavaliers* | L 84-100 | 9-10 | A. Peskine 20 | J. Chatman 5 | A. Peskine 6 |
| January 30, 2028 | WAKE FOREST DEMON DEACONS* | W 82-79 | 10-10 | B. Weaver 16 | J. Lockwood 8 | A. Peskine 15 |
| February 1, 2028 | @ #11 Louisville Cardinals* | L 64-91 | 10-11 | D. Quigley 19 | J. Lockwood 4 | B. Weaver 7 |
| February 6, 2028 | CALIFORNIA GOLDEN BEARS* | L 78-85 | 10-12 | A. Peskine 16 | J. Chatman 6 | B. Weaver 6 |
| February 8, 2028 | @ #1 Duke Blue Devils* | L 58-85 | 10-13 | J. Chatman 11 | J. Chatman 4 | D. Quigley 6 |
| February 13, 2028 | @ Boston College Eagles* | L 90-101 | 10-14 | A. Peskine 25 | J. Lockwood 7 | C. Edwards 4 |
| February 15, 2028 | @ Virginia Tech Hokies* | L 87-94 OT | 10-15 | J. Chatman 21 | J. Lockwood 7 | B. Weaver 9 |
| February 20, 2028 | @ NC-State Wolfpack* | L 56-76 | 10-16 | J. Chatman 13 | J. Lockwood 4 | B. Weaver 10 |
| February 22, 2028 | #1 DUKE BLUE DEVILS* | L 78-79 | 10-17 | A. Peskine 15 | J. Chatman 5 | A. Peskine 13 |
| February 27, 2028 | @ Notre Dame Fighting Irish* | L 69-81 | 10-18 | A. Peskine 12 | J. Lockwood 3 | A. Peskine 6 |
| March 1, 2028 | #8 LOUISVILLE CARDINALS* | W 84-77 | 11-18 | A. Peskine 20 | J. Lockwood 5 | B. Weaver 8 |
