| November 14, 2027 | OAKLAND GOLDEN GRIZZLIES NIT Season Tip-Off | W 90-78 | 1-0 | L. Hartfield 29 | W. Seegars 7 | L. Hartfield 8 |
| November 16, 2027 | DAYTON FLYERS NIT Season Tip-Off | W 66-61 | 2-0 | R. Valentine 15 | R. Valentine 8 | L. McDonald 11 |
| November 18, 2027 | #1 MARQUETTE GOLDEN EAGLES NIT Season Tip-Off | L 62-64 | 2-1 | L. McDonald 17 | R. Valentine 4 | D. Baker 9 |
| November 22, 2027 | @ #10 Michigan Wolverines | L 66-83 | 2-2 | W. Seegars 15 | W. Seegars 4 | L. Hartfield 8 |
| November 25, 2027 | UTAH UTES | W 79-72 | 3-2 | L. Hartfield 18 | W. Seegars 4 | L. McDonald 12 |
| November 29, 2027 | @ Purdue Boilermakers | L 73-80 | 3-3 | L. Hartfield 21 | W. Seegars 4 | L. McDonald 11 |
| December 2, 2027 | CHARLESTON COUGARS | L 67-74 | 3-4 | W. Seegars 18 | W. Seegars 3 | J. Tinsley 8 |
| December 6, 2027 | RHODE ISLAND RAMS | W 98-64 | 4-4 | L. Hartfield 23 | W. Seegars 9 | J. Tinsley 12 |
| December 9, 2027 | AUBURN TIGERS | W 78-61 | 5-4 | L. McDonald 16 | W. Seegars 4 | L. McDonald 11 |
| December 13, 2027 | NEW MEXICO LOBOS | W 82-61 | 6-4 | L. Hartfield 23 | W. Seegars 8 | D. Baker 10 |
| December 20, 2027 | PENN STATE NITTANY LIONS | W 82-60 | 7-4 | L. McDonald 24 | W. Seegars 5 | L. McDonald 12 |
| December 26, 2027 | #9 PITTSBURGH PANTHERS* | W 81-76 | 8-4 | L. McDonald 15 | J. Tinsley 4 | W. Seegars 10 |
| December 28, 2027 | @ NC-State Wolfpack* | W 93-69 | 9-4 | W. Seegars 33 | R. Valentine 9 | D. Baker 7 |
| January 2, 2028 | @ Syracuse Orange* | W 88-66 | 10-4 | L. McDonald 24 | D. Baker 4 | L. McDonald 12 |
| January 4, 2028 | GEORGIA TECH YELLOW JACKETS* | W 84-72 | 11-4 | W. Seegars 16 | W. Seegars 5 | D. Baker 8 |
| January 9, 2028 | @ Wake Forest Demon Deacons* | W 86-75 | 12-4 | L. McDonald 15 | W. Seegars 6 | W. Seegars 11 |
| January 11, 2028 | STANFORD CARDINAL* | W 65-54 | 13-4 | D. Baker 11 | R. Valentine 6 | L. McDonald 8 |
| January 16, 2028 | @ Virginia Tech Hokies* | W 72-61 | 14-4 | D. Baker 14 | D. Lewis 5 | L. McDonald 13 |
| January 18, 2028 | NOTRE DAME FIGHTING IRISH* | W 86-67 | 15-4 | M. Panagou 19 | W. Seegars 3 | G. Da Barrosa 7 |
| January 23, 2028 | @ Clemson Tigers* | L 64-72 | 15-5 | W. Seegars 27 | W. Seegars 3 | L. McDonald 12 |
| January 25, 2028 | @ Boston College Eagles* | W 78-68 | 16-5 | L. McDonald 16 | R. Valentine 3 | D. Baker 7 |
| January 30, 2028 | SOUTHERN METHODIST MUSTANGS* | W 79-62 | 17-5 | W. Seegars 19 | R. Valentine 6 | L. McDonald 13 |
| February 1, 2028 | @ Miami (FL) Hurricanes* | L 59-80 | 17-6 | L. McDonald 13 | W. Seegars 4 | D. Baker 9 |
| February 6, 2028 | #7 VIRGINIA CAVALIERS* | W 75-70 | 18-6 | R. Valentine 17 | W. Seegars 5 | D. Baker 7 |
| February 8, 2028 | FLORIDA STATE SEMINOLES* | L 68-74 | 18-7 | D. Baker 18 | W. Seegars 3 | L. McDonald 9 |
| February 13, 2028 | @ California Golden Bears* | L 79-87 | 18-8 | L. Hartfield 20 | W. Seegars 6 | L. McDonald 11 |
| February 15, 2028 | @ #11 Louisville Cardinals* | W 86-83 | 19-8 | D. Baker 15 | W. Seegars 8 | J. Tinsley 7 |
| February 20, 2028 | #8 NORTH CAROLINA TAR HEELS* | L 62-78 | 19-9 | L. McDonald 19 | W. Seegars 3 | L. McDonald 12 |
| February 22, 2028 | VIRGINIA TECH HOKIES* | W 96-65 | 20-9 | L. McDonald 18 | W. Seegars 7 | L. Hartfield 7 |
| February 27, 2028 | NC-STATE WOLFPACK* | W 62-61 | 21-9 | W. Seegars 19 | W. Seegars 5 | L. McDonald 11 |
| March 1, 2028 | @ Notre Dame Fighting Irish* | L 61-64 | 21-10 | L. Hartfield 17 | G. Da Barrosa 3 | L. McDonald 11 |
| March 10, 2028 | #17 LOUISVILLE CARDINALS ACC Tournament | W 83-67 | 22-10 | L. McDonald 25 | W. Seegars 7 | L. Hartfield 8 |
| March 11, 2028 | @ #15 Pittsburgh Panthers ACC Tournament | L 61-71 | 22-11 | L. McDonald 13 | W. Seegars 4 | L. McDonald 16 |
