| November 16, 2027 | TEXAS CHRISTIAN HORNED FROGS | L 78-80 | 0-1 | J. Clancy 22 | J. Norwood 7 | E. Marsh 6 |
| November 18, 2027 | LA SALLE EXPLORERS Emerald Coast Classic | W 85-39 | 1-1 | J. Clancy 26 | B. Clancy 4 | C. Bryson 15 |
| November 19, 2027 | CINCINNATI BEARCATS Emerald Coast Classic | W 103-79 | 2-1 | E. Marsh 20 | J. Clancy 7 | C. Bryson 11 |
| November 20, 2027 | #20 UC-SAN DIEGO TRITONS Emerald Coast Classic | W 92-77 | 3-1 | C. Bryson 15 | J. Norwood 5 | C. Bryson 8 |
| November 23, 2027 | WESTERN KENTUCKY HILLTOPPERS | W 88-62 | 4-1 | J. Clancy 23 | C. Bryson 7 | C. Bryson 13 |
| November 26, 2027 | @ #23 Creighton Blue Jays | W 90-72 | 5-1 | J. Norwood 26 | J. Norwood 6 | C. Bryson 19 |
| November 30, 2027 | #6 GONZAGA BULLDOGS | W 76-62 | 6-1 | E. Marsh 26 | J. Norwood 9 | E. Marsh 11 |
| December 3, 2027 | ILLINOIS STATE REDBIRDS | W 84-55 | 7-1 | J. Clancy 29 | J. Norwood 6 | C. Bryson 8 |
| December 7, 2027 | OHIO STATE BUCKEYES | W 97-64 | 8-1 | E. Porter 18 | J. Clancy 8 | C. Bryson 10 |
| December 14, 2027 | @ Arizona Wildcats | W 78-61 | 9-1 | J. Norwood 19 | J. Clancy 4 | E. Porter 10 |
| December 21, 2027 | MEMPHIS TIGERS | W 110-86 | 10-1 | C. Bryson 28 | E. Porter 7 | C. Bryson 14 |
| December 26, 2027 | PITTSBURGH PANTHERS* | W 96-62 | 11-1 | E. Marsh 20 | C. Bryson 7 | C. Bryson 9 |
| December 28, 2027 | @ Notre Dame Fighting Irish* | W 87-73 | 12-1 | E. Porter 18 | J. Norwood 6 | C. Bryson 14 |
| January 2, 2028 | VIRGINIA TECH HOKIES* | W 76-65 | 13-1 | J. Norwood 19 | B. Clancy 8 | E. Marsh 12 |
| January 4, 2028 | @ #21 North Carolina Tar Heels* | W 95-84 | 14-1 | J. Norwood 24 | B. Clancy 5 | C. Bryson 14 |
| January 9, 2028 | GEORGIA TECH YELLOW JACKETS* | W 82-58 | 15-1 | E. Marsh 20 | B. Clancy 5 | E. Marsh 9 |
| January 11, 2028 | @ Clemson Tigers* | L 65-78 | 15-2 | E. Marsh 13 | C. Wilson 4 | C. Bryson 10 |
| January 16, 2028 | WAKE FOREST DEMON DEACONS* | W 94-68 | 16-2 | E. Marsh 20 | J. Norwood 4 | C. Bryson 8 |
| January 18, 2028 | @ #6 Louisville Cardinals* | W 88-81 | 17-2 | E. Marsh 24 | J. Norwood 6 | C. Bryson 12 |
| January 23, 2028 | @ Boston College Eagles* | W 72-67 | 18-2 | E. Marsh 26 | B. Clancy 8 | C. Bryson 11 |
| January 25, 2028 | @ Stanford Cardinal* | W 83-76 | 19-2 | B. Clancy 16 | C. Bryson 5 | C. Bryson 7 |
| January 30, 2028 | @ California Golden Bears* | W 77-55 | 20-2 | J. Norwood 22 | B. Clancy 6 | B. Clancy 7 |
| February 1, 2028 | #6 VIRGINIA CAVALIERS* | W 106-96 | 21-2 | B. Clancy 23 | J. Norwood 8 | C. Bryson 14 |
| February 6, 2028 | MIAMI (FL) HURRICANES* | W 78-56 | 22-2 | M. Harvey 27 | B. Clancy 9 | B. Clancy 10 |
| February 8, 2028 | FLORIDA STATE SEMINOLES* | W 85-58 | 23-2 | E. Marsh 25 | B. Clancy 4 | C. Bryson 13 |
| February 13, 2028 | #18 SYRACUSE ORANGE* | W 80-54 | 24-2 | J. Norwood 15 | B. Clancy 3 | B. Clancy 7 |
| February 15, 2028 | @ NC-State Wolfpack* | W 62-47 | 25-2 | E. Marsh 19 | J. Norwood 4 | C. Bryson 13 |
| February 20, 2028 | @ Southern Methodist Mustangs* | W 78-71 | 26-2 | E. Marsh 26 | C. Bryson 4 | C. Bryson 8 |
| February 22, 2028 | @ Florida State Seminoles* | W 79-78 | 27-2 | J. Norwood 27 | B. Clancy 7 | E. Marsh 9 |
| February 27, 2028 | STANFORD CARDINAL* | W 96-77 | 28-2 | E. Marsh 28 | B. Clancy 11 | C. Bryson 15 |
| March 1, 2028 | NC-STATE WOLFPACK* | W 70-59 | 29-2 | E. Marsh 16 | B. Clancy 4 | B. Clancy 8 |
| March 10, 2028 | TBD ACC Tournament | - | | | | |
