| November 13, 2027 | @ Dartmouth Big Green | L 82-89 | 0-1 | M. Cross 18 | T. Rosser 4 | M. Cross 7 |
| November 23, 2027 | TEXAS-SAN ANTONIO ROADRUNNERS | L 74-94 | 0-2 | M. Cross 24 | T. Rosser 7 | T. Feaster 5 |
| November 24, 2027 | @ Howard Bison | L 56-77 | 0-3 | B. Barber 16 | T. Briggery 3 | J. Tyndell 12 |
| November 29, 2027 | @ San Diego State Aztecs | L 55-60 | 0-4 | A. Fields 14 | G. Cassel 6 | B. Barber 8 |
| December 6, 2027 | TULSA GOLDEN HURRICANES | W 89-84 OT | 1-4 | T. Rosser 24 | B. Barber 5 | T. Feaster 8 |
| December 9, 2027 | @ New Hampshire Wildcats | L 92-101 | 1-5 | B. Barber 24 | T. Rosser 6 | T. Feaster 8 |
| December 16, 2027 | LINDENWOOD LIONS | W 86-81 | 2-5 | M. Cross 20 | G. Cassel 5 | A. Fields 8 |
| December 20, 2027 | @ Missouri Tigers | L 57-80 | 2-6 | B. Barber 12 | C. Webber 4 | J. Tyndell 5 |
| December 23, 2027 | NC-ASHEVILLE BULLDOGS Empire Classic | L 91-92 | 2-7 | T. Rosser 22 | T. Rosser 6 | J. Tyndell 9 |
| December 26, 2027 | @ Illinois-Chicago Flames* | W 101-87 | 3-7 | M. Cross 17 | T. Rosser 7 | J. Tyndell 9 |
| December 30, 2027 | VALPARAISO BEACONS* | L 67-82 | 3-8 | C. Webber 16 | G. Cassel 5 | T. Feaster 9 |
| January 2, 2028 | @ Northern Iowa Panthers* | L 76-98 | 3-9 | M. Cross 18 | T. Rosser 5 | J. Tyndell 5 |
| January 4, 2028 | SOUTHERN ILLINOIS SALUKIS* | W 94-83 | 4-9 | M. Cross 20 | M. Cross 4 | B. Barber 7 |
| January 6, 2028 | BELMONT BRUINS* | W 87-76 | 5-9 | M. Cross 27 | T. Rosser 6 | J. Tyndell 7 |
| January 11, 2028 | @ Bradley Braves* | L 64-68 | 5-10 | T. Briggery 17 | B. Barber 5 | B. Barber 6 |
| January 13, 2028 | @ Indiana State Sycamores* | L 63-74 | 5-11 | M. Cross 15 | T. Rosser 4 | T. Feaster 6 |
| January 18, 2028 | MURRAY STATE RACERS* | W 83-76 | 6-11 | M. Cross 27 | T. Rosser 8 | T. Feaster 10 |
| January 23, 2028 | @ Southern Illinois Salukis* | W 87-83 | 7-11 | M. Cross 23 | T. Rosser 4 | B. Barber 9 |
| January 27, 2028 | ILLINOIS STATE REDBIRDS* | L 72-86 | 7-12 | M. Cross 27 | T. Rosser 6 | B. Barber 7 |
| January 30, 2028 | EVANSVILLE PURPLE ACES* | W 82-75 | 8-12 | M. Cross 19 | G. Cassel 6 | J. Tyndell 9 |
| February 1, 2028 | @ Belmont Bruins* | L 69-89 | 8-13 | B. Barber 10 | T. Rosser 6 | M. Cross 8 |
| February 3, 2028 | @ Valparaiso Beacons* | L 79-85 | 8-14 | T. Briggery 15 | T. Rosser 5 | M. Cross 5 |
| February 8, 2028 | INDIANA STATE SYCAMORES* | W 81-68 | 9-14 | M. Cross 28 | T. Rosser 4 | M. Cross 8 |
| February 10, 2028 | BRADLEY BRAVES* | L 67-77 | 9-15 | M. Cross 16 | T. Rosser 4 | A. Fields 7 |
| February 15, 2028 | @ Illinois State Redbirds* | L 72-82 | 9-16 | M. Cross 30 | T. Rosser 6 | T. Feaster 6 |
| February 17, 2028 | @ Evansville Purple Aces* | L 79-97 | 9-17 | M. Cross 18 | T. Rosser 4 | B. Barber 9 |
| February 22, 2028 | NORTHERN IOWA PANTHERS* | L 84-87 OT | 9-18 | T. Rosser 16 | T. Rosser 4 | B. Barber 8 |
| February 24, 2028 | ILLINOIS-CHICAGO FLAMES* | L 55-63 | 9-19 | M. Cross 18 | J. Tyndell 6 | J. Tyndell 8 |
| March 3, 2028 | @ Murray State Racers* | L 63-83 | 9-20 | M. Cross 15 | G. Cassel 4 | J. Tyndell 5 |
| March 6, 2028 | @ Illinois-Chicago Flames (9-20, 7-6 Home) MVC Tournament | - | | | | |
