| November 16, 2025 | SAN DIEGO TOREROS | W 89-75 | 1-0 | B. Bass 20 | B. Bass 6 | M. Mast 7 |
| November 19, 2025 | @ Nevada Wolfpack | W 82-77 | 2-0 | M. Jones 19 | C. Fields 2 | M. Jones 7 |
| November 23, 2025 | NORTHERN KENTUCKY NORSE | W 82-70 | 3-0 | J. Young 18 | C. Fields 7 | M. Mast 6 |
| November 26, 2025 | LOYOLA (IL) RAMBLERS | W 95-93 OT | 4-0 | M. Jones 30 | C. Fields 5 | M. Rush 7 |
| November 30, 2025 | @ Virginia Cavaliers | L 102-110 OT | 4-1 | J. Young 23 | J. Young 5 | M. Mast 10 |
| December 3, 2025 | @ Oklahoma State Cowboys | L 45-68 | 4-2 | M. Jones 15 | J. Young 4 | M. Mast 10 |
| December 7, 2025 | AKRON ZIPS | W 85-71 | 5-2 | B. Bass 18 | J. Young 9 | M. Jones 10 |
| December 14, 2025 | #6 ALABAMA CRIMSON TIDE | L 58-66 | 5-3 | J. Young 12 | J. Young 4 | D. Kern 7 |
| December 21, 2025 | @ Kansas Jayhawks (10-1, 6-1 Home) | - | | | | |
| December 26, 2025 | @ Xavier Musketeers (5-2, 0-0, 4-1 Home)* | - | | | | |
| December 28, 2025 | ST. JOHNS RED STORM (5-5, 0-0, 0-2 Away)* | - | | | | |
| December 30, 2025 | BUTLER BULLDOGS (7-2, 0-0, 0-1 Away)* | - | | | | |
| January 4, 2026 | @ Seton Hall Pirates (7-2, 0-0, 6-0 Home)* | - | | | | |
| January 11, 2026 | CONNECTICUT HUSKIES (11-0, 0-0, 0-0 Away)* | - | | | | |
| January 13, 2026 | MARQUETTE GOLDEN EAGLES (5-3, 0-0, 0-2 Away)* | - | | | | |
| January 20, 2026 | @ Georgetown Hoyas (1-7, 0-0, 1-2 Home)* | - | | | | |
| January 23, 2026 | @ Providence Friars (9-1, 0-0, 5-0 Home)* | - | | | | |
| January 25, 2026 | VILLANOVA WILDCATS (6-1, 0-0, 2-1 Away)* | - | | | | |
| January 27, 2026 | SETON HALL PIRATES (7-2, 0-0, 0-1 Away)* | - | | | | |
| February 1, 2026 | CREIGHTON BLUE JAYS (6-3, 0-0, 0-1 Away)* | - | | | | |
| February 3, 2026 | XAVIER MUSKETEERS (5-2, 0-0, 1-1 Away)* | - | | | | |
| February 8, 2026 | @ Marquette Golden Eagles (5-3, 0-0, 5-0 Home)* | - | | | | |
| February 10, 2026 | @ Connecticut Huskies (11-0, 0-0, 7-0 Home)* | - | | | | |
| February 15, 2026 | @ Creighton Blue Jays (6-3, 0-0, 5-1 Home)* | - | | | | |
| February 17, 2026 | @ Villanova Wildcats (6-1, 0-0, 4-0 Home)* | - | | | | |
| February 22, 2026 | GEORGETOWN HOYAS (1-7, 0-0, 0-4 Away)* | - | | | | |
| February 24, 2026 | PROVIDENCE FRIARS (9-1, 0-0, 1-1 Away)* | - | | | | |
| March 1, 2026 | @ Butler Bulldogs (7-2, 0-0, 6-0 Home)* | - | | | | |
| March 3, 2026 | @ St. Johns Red Storm (5-5, 0-0, 3-2 Home)* | - | | | | |
