| November 13, 2027 | GEORGE WASHINGTON REVOLUTIONARIES Legends Classic | W 91-70 | 1-0 | D. Williams 36 | J. Patton 7 | J. Crawford 6 |
| November 15, 2027 | #11 VIRGINIA CAVALIERS Legends Classic | W 85-82 | 2-0 | D. Williams 22 | D. Williams 6 | R. Cunningham 16 |
| November 17, 2027 | @ #5 Gonzaga Bulldogs Legends Classic | L 77-93 | 2-1 | K. Nealy 20 | D. Williams 8 | R. Cunningham 13 |
| November 23, 2027 | @ Temple Owls | W 84-74 | 3-1 | D. Williams 26 | J. Patton 4 | J. Crawford 8 |
| November 26, 2027 | #6 DUKE BLUE DEVILS | L 72-90 | 3-2 | D. Williams 26 | D. Williams 4 | R. Cunningham 6 |
| November 30, 2027 | SEATTLE REDHAWKS | W 74-56 | 4-2 | D. Williams 27 | J. Patton 6 | R. Cunningham 16 |
| December 3, 2027 | #10 LOUISVILLE CARDINALS | W 74-66 | 5-2 | D. Williams 24 | J. Patton 3 | J. Crawford 9 |
| December 7, 2027 | WEST VIRGINIA MOUNTAINEERS | W 82-68 | 6-2 | K. Nealy 24 | D. Williams 8 | R. Cunningham 14 |
| December 10, 2027 | #4 BRIGHAM YOUNG COUGARS | W 87-76 | 7-2 | K. Nealy 22 | J. Patton 6 | R. Cunningham 9 |
| December 14, 2027 | LIBERTY FLAMES | W 76-59 | 8-2 | D. Williams 17 | D. Williams 5 | R. Cunningham 8 |
| December 21, 2027 | MURRAY STATE RACERS | W 95-62 | 9-2 | D. Williams 23 | J. Patton 8 | R. Cunningham 8 |
| December 26, 2027 | BUTLER BULLDOGS* | W 70-52 | 10-2 | D. Williams 21 | J. Patton 5 | J. Crawford 11 |
| December 30, 2027 | @ #23 Marquette Golden Eagles* | W 102-81 | 11-2 | J. Crawford 28 | D. Williams 5 | J. Crawford 9 |
| January 2, 2028 | XAVIER MUSKETEERS* | W 98-77 | 12-2 | D. Williams 29 | D. Williams 9 | J. Crawford 10 |
| January 4, 2028 | #8 CONNECTICUT HUSKIES* | W 98-82 | 13-2 | D. Williams 25 | D. Williams 6 | R. Cunningham 10 |
| January 6, 2028 | @ St. Johns Red Storm* | W 74-68 | 14-2 | D. Williams 25 | K. Nealy 10 | J. Crawford 9 |
| January 11, 2028 | @ Seton Hall Pirates* | W 74-63 | 15-2 | D. Williams 18 | D. Williams 5 | R. Cunningham 17 |
| January 16, 2028 | @ Providence Friars* | W 87-67 | 16-2 | R. Cunningham 24 | D. Williams 9 | R. Cunningham 10 |
| January 18, 2028 | VILLANOVA WILDCATS* | W 71-52 | 17-2 | J. Patton 18 | J. Patton 4 | R. Cunningham 11 |
| January 20, 2028 | GEORGETOWN HOYAS* | L 63-76 | 17-3 | D. Williams 23 | J. Patton 5 | R. Cunningham 12 |
| January 25, 2028 | @ DePaul Blue Demons* | W 83-63 | 18-3 | K. Nealy 19 | D. Williams 9 | R. Cunningham 17 |
| January 27, 2028 | @ #11 Connecticut Huskies* | L 87-103 | 18-4 | D. Williams 35 | D. Williams 7 | R. Cunningham 5 |
| February 1, 2028 | ST. JOHNS RED STORM* | W 79-70 | 19-4 | D. Williams 24 | D. Williams 6 | J. Crawford 7 |
| February 3, 2028 | MARQUETTE GOLDEN EAGLES* | W 66-65 | 20-4 | J. Patton 17 | D. Williams 3 | J. Crawford 9 |
| February 8, 2028 | @ Georgetown Hoyas* | W 86-56 | 21-4 | J. Crawford 27 | D. Williams 5 | R. Cunningham 12 |
| February 10, 2028 | @ Villanova Wildcats* | W 66-64 | 22-4 | K. Nealy 21 | J. Patton 8 | R. Cunningham 8 |
| February 17, 2028 | DEPAUL BLUE DEMONS* | L 65-69 | 22-5 | K. Nealy 16 | J. Patton 6 | A. Haralson 7 |
| February 24, 2028 | PROVIDENCE FRIARS* | W 74-64 | 23-5 | J. Patton 25 | D. Williams 6 | R. Cunningham 10 |
| February 27, 2028 | SETON HALL PIRATES* | W 93-91 OT | 24-5 | D. Williams 28 | J. Patton 10 | J. Crawford 10 |
| March 1, 2028 | @ Butler Bulldogs* | W 76-55 | 25-5 | D. Williams 21 | D. Williams 7 | R. Cunningham 9 |
| March 3, 2028 | @ Xavier Musketeers* | W 91-69 | 26-5 | D. Williams 25 | D. Williams 5 | A. Haralson 8 |
| March 10, 2028 | TBD Big East Tournament | - | | | | |
