| November 13, 2027 | CANISIUS GOLDEN GRIFFINS | W 82-81 | 1-0 | D. Lang 18 | D. Treadwell 7 | N. DeGray 7 |
| November 15, 2027 | @ South Alabama Jaguars | W 86-82 | 2-0 | K. Brady 28 | D. Treadwell 6 | C. Burleston 9 |
| November 18, 2027 | @ Campbell Fighting Camels | L 62-83 | 2-1 | K. Brady 21 | D. Stevenson 5 | K. Brady 7 |
| November 20, 2027 | @ Houston Christian Huskies | L 73-87 | 2-2 | N. DeGray 21 | C. Burleston 5 | C. Burleston 6 |
| November 22, 2027 | @ Georgia Tech Yellow Jackets | L 67-87 | 2-3 | C. Burleston 16 | D. Treadwell 7 | N. DeGray 11 |
| November 25, 2027 | @ Rutgers Scarlet Knights | L 58-73 | 2-4 | K. Brady 20 | N. DeGray 5 | N. DeGray 10 |
| November 29, 2027 | @ Howard Bison | W 92-77 | 3-4 | K. Brady 33 | D. Stevenson 6 | N. DeGray 11 |
| December 1, 2027 | @ Cal St. Northridge Matadors | L 69-97 | 3-5 | K. Brady 23 | D. Treadwell 5 | N. DeGray 8 |
| December 6, 2027 | @ Akron Zips | L 63-77 | 3-6 | D. Treadwell 15 | D. Treadwell 6 | N. DeGray 9 |
| December 9, 2027 | @ Toledo Rockets | L 77-90 | 3-7 | N. DeGray 22 | D. Treadwell 4 | N. DeGray 6 |
| December 14, 2027 | IDAHO STATE BENGALS | L 82-95 | 3-8 | D. Treadwell 14 | D. Treadwell 5 | D. Treadwell 5 |
| December 16, 2027 | @ Tennessee State Tigers | W 78-68 | 4-8 | K. Brady 24 | D. Treadwell 6 | C. Burleston 10 |
| December 19, 2027 | GREEN BAY PHOENIX | W 97-87 | 5-8 | N. DeGray 34 | D. Treadwell 10 | N. DeGray 8 |
| December 23, 2027 | SOUTHERN ILLINOIS SALUKIS | L 78-88 | 5-9 | N. DeGray 19 | D. Treadwell 5 | C. Burleston 15 |
| December 27, 2027 | SANTA CLARA BRONCOS | W 96-95 | 6-9 | K. Brady 25 | D. Treadwell 8 | N. DeGray 8 |
| January 10, 2028 | CORNELL BIG RED* | L 93-100 | 6-10 | N. DeGray 34 | D. Treadwell 9 | N. DeGray 7 |
| January 13, 2028 | @ Harvard Crimson* | L 51-76 | 6-11 | N. DeGray 20 | D. Treadwell 2 | N. DeGray 7 |
| January 17, 2028 | DARTMOUTH BIG GREEN* | L 78-86 OT | 6-12 | K. Brady 30 | D. Treadwell 10 | J. Kemp 7 |
| January 20, 2028 | @ Pennsylvania Quakers* | L 63-86 | 6-13 | N. DeGray 17 | D. Treadwell 5 | N. DeGray 7 |
| January 24, 2028 | YALE BULLDOGS* | L 81-96 | 6-14 | K. Brady 21 | D. Stevenson 6 | N. DeGray 7 |
| January 27, 2028 | @ Princeton Tigers* | L 68-72 | 6-15 | K. Brady 15 | D. Treadwell 4 | D. Treadwell 11 |
| January 31, 2028 | BROWN BEARS* | W 83-64 | 7-15 | K. Brady 25 | N. DeGray 6 | C. Burleston 8 |
| February 3, 2028 | @ Cornell Big Red* | L 83-102 | 7-16 | D. Treadwell 16 | D. Treadwell 8 | V. Benson 8 |
| February 7, 2028 | HARVARD CRIMSON* | W 95-88 | 8-16 | K. Brady 31 | K. Brady 6 | N. DeGray 7 |
| February 10, 2028 | @ Dartmouth Big Green* | W 79-71 | 9-16 | K. Brady 17 | D. Treadwell 6 | N. DeGray 9 |
| February 14, 2028 | PENNSYLVANIA QUAKERS* | W 76-67 | 10-16 | N. DeGray 14 | D. Treadwell 8 | N. DeGray 11 |
| February 17, 2028 | @ Yale Bulldogs* | L 61-94 | 10-17 | D. Treadwell 16 | D. Treadwell 6 | C. Burleston 6 |
| February 21, 2028 | PRINCETON TIGERS* | W 87-64 | 11-17 | V. Benson 27 | D. Treadwell 8 | V. Benson 8 |
| February 24, 2028 | @ Brown Bears* | L 86-100 | 11-18 | B. Nixon 15 | V. Benson 4 | N. DeGray 6 |
