| November 19, 2027 | BOSTON COLLEGE EAGLES | L 59-77 | 0-1 | B. Lewis 17 | J. Baker 3 | J. Bullock 10 |
| November 22, 2027 | @ Texas Longhorns | L 75-92 | 0-2 | J. Bullock 16 | J. Baker 3 | J. Bullock 8 |
| November 24, 2027 | KENNESAW STATE OWLS | W 72-54 | 1-2 | B. Lewis 16 | J. Baker 7 | J. Bullock 12 |
| November 30, 2027 | WAKE FOREST DEMON DEACONS | W 83-71 | 2-2 | B. Lewis 14 | J. Baker 10 | J. Miller 8 |
| December 2, 2027 | NJIT HIGHLANDERS | W 82-67 | 3-2 | J. McFadden 29 | J. Baker 8 | J. McFadden 12 |
| December 6, 2027 | CAL POLY MUSTANGS | W 99-62 | 4-2 | J. Bullock 22 | J. Baker 8 | B. Lewis 9 |
| December 8, 2027 | NORTHERN COLORADO BEARS | W 72-49 | 5-2 | B. Lewis 18 | J. Baker 8 | J. Bullock 10 |
| December 13, 2027 | @ La Salle Explorers | W 79-77 | 6-2 | J. Baker 22 | J. Baker 5 | J. Bullock 8 |
| December 23, 2027 | MCNEESE STATE COWBOYS Empire Classic | L 63-72 | 6-3 | B. Lewis 20 | J. Baker 3 | B. Lewis 14 |
| December 28, 2027 | @ Arizona State Sun Devils* | W 87-79 | 7-3 | J. Baker 24 | J. Bullock 3 | B. Lewis 9 |
| January 2, 2028 | CINCINNATI BEARCATS* | L 72-73 | 7-4 | J. McFadden 17 | J. Baker 4 | B. Lewis 8 |
| January 4, 2028 | OKLAHOMA STATE COWBOYS* | L 62-65 | 7-5 | J. Baker 18 | J. Baker 5 | B. Lewis 11 |
| January 6, 2028 | @ Arizona Wildcats* | L 48-77 | 7-6 | J. Baker 13 | J. Baker 4 | J. Bullock 10 |
| January 9, 2028 | @ #4 Brigham Young Cougars* | L 63-83 | 7-7 | J. Bullock 18 | J. Miller 3 | J. Bullock 7 |
| January 13, 2028 | TEXAS CHRISTIAN HORNED FROGS* | W 63-60 | 8-7 | Y. Machem 18 | J. Baker 7 | J. Bullock 15 |
| January 18, 2028 | @ #18 Houston Cougars* | L 62-67 | 8-8 | B. Lewis 22 | Y. Machem 5 | J. Bullock 10 |
| January 20, 2028 | #4 KANSAS JAYHAWKS* | L 66-75 | 8-9 | J. McFadden 24 | J. Baker 5 | J. Bullock 7 |
| January 25, 2028 | @ Cincinnati Bearcats* | L 98-106 OT | 8-10 | J. Baker 25 | J. Bullock 5 | J. Bullock 12 |
| January 27, 2028 | WEST VIRGINIA MOUNTAINEERS* | L 78-88 | 8-11 | B. Lewis 24 | J. Baker 11 | J. Bullock 8 |
| February 1, 2028 | KANSAS STATE WILDCATS* | L 78-89 | 8-12 | T. Swift 19 | J. Baker 9 | B. Lewis 12 |
| February 3, 2028 | @ Baylor Bears* | L 70-80 | 8-13 | J. Bullock 17 | J. Baker 3 | J. Bullock 9 |
| February 8, 2028 | HOUSTON COUGARS* | L 79-95 | 8-14 | J. McFadden 16 | J. Baker 3 | B. Lewis 10 |
| February 10, 2028 | @ Oklahoma State Cowboys* | L 76-77 | 8-15 | B. Lewis 18 | J. Baker 6 | J. McFadden 7 |
| February 15, 2028 | @ Texas Tech Red Raiders* | L 54-64 | 8-16 | B. Lewis 14 | J. Baker 4 | B. Lewis 11 |
| February 20, 2028 | UTAH UTES* | W 96-80 | 9-16 | J. Bullock 26 | J. Miller 6 | J. Miller 10 |
| February 22, 2028 | #12 IOWA STATE CYCLONES* | L 101-102 | 9-17 | J. Baker 20 | J. Baker 5 | J. Bullock 16 |
| February 24, 2028 | @ #5 Kansas Jayhawks* | L 60-77 | 9-18 | B. Lewis 16 | J. Baker 2 | J. Miller 6 |
| March 1, 2028 | TEXAS TECH RED RAIDERS* | L 66-81 | 9-19 | J. Bullock 17 | J. Baker 11 | J. Bullock 11 |
| March 3, 2028 | @ Central Florida Knights* | L 81-87 | 9-20 | J. Bullock 19 | J. Baker 3 | J. McFadden 6 |
| March 8, 2028 | @ Oklahoma State Cowboys (16-15, 9-7 Home) Big 12 Tournament | - | | | | |
