| November 13, 2027 | OKLAHOMA SOONERS | W 102-87 | 1-0 | S. Tony-El 22 | T. Gray 10 | M. Fleming 7 |
| November 18, 2027 | @ Indiana Hoosiers Emerald Coast Classic | W 87-81 | 2-0 | S. Tony-El 27 | T. Gray 7 | M. Fleming 11 |
| November 19, 2027 | @ #1 Duke Blue Devils Emerald Coast Classic | L 79-103 | 2-1 | M. Obradovic 15 | T. Gray 7 | S. Tony-El 6 |
| November 22, 2027 | MD-BALTIMORE COUNTY RETRIEVERS | W 81-77 | 3-1 | S. Tony-El 30 | T. Gray 10 | M. Obradovic 10 |
| November 25, 2027 | WESTERN MICHIGAN BRONCOS | W 82-74 | 4-1 | M. Fleming 16 | T. Gray 8 | C. Nelson 9 |
| November 30, 2027 | @ Charlotte 49ers | L 75-90 | 4-2 | M. Obradovic 21 | S. Tony-El 4 | C. Nelson 11 |
| December 7, 2027 | OMAHA MAVERICKS | W 99-89 | 5-2 | T. Gray 21 | T. Gray 6 | M. Fleming 11 |
| December 13, 2027 | @ Xavier Musketeers | L 79-101 | 5-3 | S. Tony-El 21 | T. Gray 9 | C. Nelson 7 |
| December 16, 2027 | NEW HAMPSHIRE WILDCATS | L 90-105 | 5-4 | M. Obradovic 26 | T. Gray 6 | R. Peskine 4 |
| December 23, 2027 | RADFORD HIGHLANDERS | W 91-76 | 6-4 | T. Gray 31 | T. Gray 5 | M. Fleming 6 |
| December 28, 2027 | CENTRAL FLORIDA KNIGHTS* | W 71-66 | 7-4 | S. Tony-El 16 | T. Gray 5 | M. Obradovic 10 |
| January 2, 2028 | @ Colorado Buffaloes* | W 73-72 | 8-4 | S. Tony-El 21 | T. Gray 7 | T. Gray 5 |
| January 4, 2028 | #4 BRIGHAM YOUNG COUGARS* | L 77-112 | 8-5 | M. Obradovic 14 | T. Gray 4 | M. Fleming 4 |
| January 6, 2028 | @ Kansas State Wildcats* | L 78-104 | 8-6 | R. Peskine 23 | T. Gray 5 | M. Obradovic 9 |
| January 11, 2028 | @ #19 Houston Cougars* | L 69-75 | 8-7 | S. Tony-El 13 | T. Gray 8 | M. Fleming 10 |
| January 13, 2028 | #11 IOWA STATE CYCLONES* | L 99-115 | 8-8 | S. Tony-El 32 | T. Gray 5 | S. Tony-El 7 |
| January 18, 2028 | @ #4 Kansas Jayhawks* | L 68-80 | 8-9 | R. Peskine 14 | T. Gray 6 | M. Fleming 7 |
| January 20, 2028 | TEXAS CHRISTIAN HORNED FROGS* | W 91-78 | 9-9 | S. Tony-El 21 | S. Tony-El 5 | R. Peskine 11 |
| January 25, 2028 | COLORADO BUFFALOES* | W 106-98 OT | 10-9 | S. Tony-El 28 | T. Gray 9 | M. Fleming 12 |
| January 27, 2028 | @ Baylor Bears* | L 77-91 | 10-10 | C. Nelson 11 | T. Gray 4 | C. Nelson 8 |
| January 30, 2028 | #19 HOUSTON COUGARS* | W 96-83 | 11-10 | S. Tony-El 23 | T. Gray 6 | M. Fleming 12 |
| February 3, 2028 | @ #8 Iowa State Cyclones* | L 89-102 | 11-11 | S. Tony-El 26 | T. Gray 6 | M. Fleming 6 |
| February 8, 2028 | OKLAHOMA STATE COWBOYS* | W 83-58 | 12-11 | S. Tony-El 25 | T. Gray 4 | M. Obradovic 6 |
| February 10, 2028 | @ Utah Utes* | W 72-61 | 13-11 | S. Tony-El 17 | T. Gray 6 | M. Fleming 6 |
| February 15, 2028 | @ West Virginia Mountaineers* | L 79-95 | 13-12 | S. Tony-El 21 | T. Gray 10 | M. Obradovic 7 |
| February 17, 2028 | TEXAS TECH RED RAIDERS* | W 103-79 | 14-12 | T. Barrett 22 | T. Gray 7 | C. Nelson 6 |
| February 20, 2028 | @ Oklahoma State Cowboys* | W 89-82 | 15-12 | T. Gray 16 | T. Gray 5 | M. Obradovic 7 |
| February 24, 2028 | ARIZONA STATE SUN DEVILS* | L 89-101 | 15-13 | S. Tony-El 24 | T. Gray 5 | C. Nelson 9 |
| February 27, 2028 | @ Texas Christian Horned Frogs* | L 89-92 | 15-14 | T. Gray 23 | T. Gray 6 | M. Fleming 6 |
| March 3, 2028 | #15 ARIZONA WILDCATS* | L 61-77 | 15-15 | S. Tony-El 15 | T. Gray 3 | M. Fleming 7 |
| March 9, 2028 | TBD Big 12 Tournament | - | | | | |
