| November 14, 2027 | @ George Washington Revolutionaries | W 71-56 | 1-0 | D. Jonzen 13 | J. Gravitt 7 | D. Jonzen 6 |
| November 18, 2027 | DARTMOUTH BIG GREEN | W 76-50 | 2-0 | D. Jonzen 19 | J. Gravitt 6 | G. Gomez 6 |
| November 21, 2027 | @ Wright State Raiders WSSN Classic | L 58-74 | 2-1 | D. Jonzen 16 | J. Gravitt 4 | D. Jonzen 7 |
| November 25, 2027 | NEW ORLEANS PRIVATEERS | L 75-95 | 2-2 | D. Jonzen 26 | J. Kapono 7 | D. Jonzen 7 |
| November 29, 2027 | ERIE FREIGHTERS | W 63-51 | 3-2 | D. Jonzen 19 | J. Kapono 6 | D. Jonzen 11 |
| December 7, 2027 | IONA GAELS | W 76-65 | 4-2 | J. Gravitt 16 | J. Gravitt 5 | G. Gomez 7 |
| December 9, 2027 | SEATTLE REDHAWKS | W 66-55 | 5-2 | D. Jonzen 22 | J. Gravitt 6 | M. Thomas 10 |
| December 13, 2027 | TEXAS SOUTHERN TIGERS | L 64-84 | 5-3 | J. Gravitt 15 | J. Gravitt 3 | J. Gravitt 3 |
| December 20, 2027 | COLGATE RAIDERS | W 80-78 | 6-3 | D. Jonzen 25 | G. Gomez 4 | G. Gomez 7 |
| December 26, 2027 | @ Stanford Cardinal* | W 79-73 | 7-3 | M. Thomas 19 | J. Gravitt 8 | M. Thomas 10 |
| December 28, 2027 | GEORGIA TECH YELLOW JACKETS* | W 96-86 | 8-3 | J. Kapono 29 | J. Gravitt 5 | G. Gomez 7 |
| January 2, 2028 | @ #11 Louisville Cardinals* | L 73-90 | 8-4 | D. Jonzen 21 | J. Gravitt 4 | S. Spurgeon 6 |
| January 4, 2028 | @ Clemson Tigers* | L 54-76 | 8-5 | J. Kapono 17 | J. Gravitt 5 | S. Spurgeon 8 |
| January 9, 2028 | @ NC-State Wolfpack* | L 55-66 | 8-6 | J. Gravitt 11 | J. Gravitt 5 | S. Spurgeon 9 |
| January 11, 2028 | @ Wake Forest Demon Deacons* | L 71-90 | 8-7 | D. Jonzen 19 | J. Gravitt 5 | D. Jonzen 7 |
| January 16, 2028 | NOTRE DAME FIGHTING IRISH* | L 77-85 OT | 8-8 | D. Jonzen 19 | J. Kapono 5 | J. Gravitt 7 |
| January 18, 2028 | @ Miami (FL) Hurricanes* | L 72-82 | 8-9 | D. Jonzen 34 | J. Gravitt 3 | D. Jonzen 9 |
| January 23, 2028 | @ Southern Methodist Mustangs* | W 78-71 | 9-9 | J. Kapono 18 | J. Gravitt 5 | S. Spurgeon 13 |
| January 25, 2028 | #6 VIRGINIA CAVALIERS* | L 70-86 | 9-10 | D. Jonzen 29 | J. Kapono 4 | D. Jonzen 12 |
| January 30, 2028 | BOSTON COLLEGE EAGLES* | L 81-96 | 9-11 | J. Kapono 14 | J. Gravitt 5 | D. Jonzen 9 |
| February 1, 2028 | SYRACUSE ORANGE* | W 83-74 | 10-11 | D. Jonzen 44 | J. Gravitt 9 | D. Jonzen 9 |
| February 6, 2028 | @ Florida State Seminoles* | L 62-72 | 10-12 | D. Jonzen 24 | J. Kapono 5 | D. Jonzen 9 |
| February 8, 2028 | VIRGINIA TECH HOKIES* | W 72-63 | 11-12 | D. Jonzen 22 | J. Kapono 5 | D. Jonzen 7 |
| February 13, 2028 | #8 DUKE BLUE DEVILS* | W 87-79 | 12-12 | D. Jonzen 26 | J. Gravitt 3 | S. Spurgeon 6 |
| February 15, 2028 | @ #10 North Carolina Tar Heels* | L 37-51 | 12-13 | D. Jonzen 12 | J. Gravitt 4 | S. Spurgeon 9 |
| February 20, 2028 | #15 PITTSBURGH PANTHERS* | L 78-99 | 12-14 | D. Jonzen 23 | G. Gomez 6 | D. Jonzen 8 |
| February 22, 2028 | @ #15 Pittsburgh Panthers* | L 75-96 | 12-15 | D. Jonzen 35 | J. Gravitt 5 | G. Gomez 12 |
| February 27, 2028 | CLEMSON TIGERS* | L 75-85 | 12-16 | J. Gravitt 19 | J. Kapono 5 | S. Spurgeon 8 |
| March 1, 2028 | #16 LOUISVILLE CARDINALS* | L 51-54 | 12-17 | J. Gravitt 17 | D. Jonzen 2 | G. Gomez 10 |
