| November 14, 2027 | @ VA Commonwealth Rams | L 82-89 | 0-1 | P. Flint 25 | F. Howard 6 | K. Johnson 8 |
| November 18, 2027 | ORAL ROBERTS GOLDEN EAGLES Sunshine Slam | W 71-66 | 1-1 | I. Cunningham 15 | F. Howard 6 | K. Johnson 6 |
| November 19, 2027 | MISSISSIPPI REBELS Sunshine Slam | W 67-63 | 2-1 | P. Flint 13 | P. Flint 2 | D. Meeks 8 |
| November 20, 2027 | #18 IOWA STATE CYCLONES Sunshine Slam | W 71-64 | 3-1 | P. Flint 29 | F. Howard 10 | D. Meeks 16 |
| November 22, 2027 | @ #24 Michigan State Spartans | L 61-68 | 3-2 | K. Johnson 10 | F. Howard 5 | K. Johnson 6 |
| November 25, 2027 | MILWAUKEE PANTHERS | L 63-66 | 3-3 | P. Flint 24 | P. Flint 6 | D. Meeks 9 |
| November 29, 2027 | UC-IRVINE ANTEATERS | W 80-66 | 4-3 | P. Flint 22 | F. Howard 6 | D. Meeks 9 |
| December 2, 2027 | @ #10 Gonzaga Bulldogs | L 52-69 | 4-4 | F. Howard 11 | T. Wallace 4 | D. Meeks 9 |
| December 6, 2027 | #23 MINNESOTA GOLDEN GOPHERS | W 77-67 | 5-4 | F. Howard 14 | F. Howard 3 | D. Meeks 14 |
| December 13, 2027 | @ Southern California Trojans | W 92-86 | 6-4 | K. Johnson 23 | F. Howard 9 | D. Meeks 9 |
| December 19, 2027 | RICHMOND SPIDERS (7-2, 1-2 Away) | - | | | | |
| December 26, 2027 | PROVIDENCE FRIARS (7-3, 0-0, 1-0 Away)* | - | | | | |
| December 30, 2027 | @ DePaul Blue Demons (6-2, 0-0, 5-0 Home)* | - | | | | |
| January 2, 2028 | SETON HALL PIRATES (9-1, 0-0, 1-0 Away)* | - | | | | |
| January 4, 2028 | CONNECTICUT HUSKIES (2-6, 0-0, 0-1 Away)* | - | | | | |
| January 6, 2028 | @ Georgetown Hoyas (8-0, 0-0, 7-0 Home)* | - | | | | |
| January 11, 2028 | @ Marquette Golden Eagles (10-1, 0-0, 5-1 Home)* | - | | | | |
| January 16, 2028 | @ Creighton Blue Jays (8-2, 0-0, 6-1 Home)* | - | | | | |
| January 18, 2028 | ST. JOHNS RED STORM (4-4, 0-0, 1-1 Away)* | - | | | | |
| January 20, 2028 | VILLANOVA WILDCATS (7-0, 0-0, 3-0 Away)* | - | | | | |
| January 25, 2028 | @ Xavier Musketeers (5-4, 0-0, 2-2 Home)* | - | | | | |
| January 27, 2028 | @ Connecticut Huskies (2-6, 0-0, 1-4 Home)* | - | | | | |
| February 1, 2028 | GEORGETOWN HOYAS (8-0, 0-0, 1-0 Away)* | - | | | | |
| February 3, 2028 | DEPAUL BLUE DEMONS (6-2, 0-0, 1-2 Away)* | - | | | | |
| February 8, 2028 | @ Villanova Wildcats (7-0, 0-0, 4-0 Home)* | - | | | | |
| February 10, 2028 | @ St. Johns Red Storm (4-4, 0-0, 3-2 Home)* | - | | | | |
| February 17, 2028 | XAVIER MUSKETEERS (5-4, 0-0, 2-1 Away)* | - | | | | |
| February 24, 2028 | CREIGHTON BLUE JAYS (8-2, 0-0, 0-0 Away)* | - | | | | |
| February 27, 2028 | MARQUETTE GOLDEN EAGLES (10-1, 0-0, 1-0 Away)* | - | | | | |
| March 1, 2028 | @ Providence Friars (7-3, 0-0, 3-3 Home)* | - | | | | |
| March 3, 2028 | @ Seton Hall Pirates (9-1, 0-0, 5-1 Home)* | - | | | | |
