| November 14, 2027 | @ VA Commonwealth Rams | L 82-89 | 0-1 | P. Flint 25 | F. Howard 6 | K. Johnson 8 |
| November 18, 2027 | ORAL ROBERTS GOLDEN EAGLES Sunshine Slam | W 71-66 | 1-1 | I. Cunningham 15 | F. Howard 6 | K. Johnson 6 |
| November 19, 2027 | MISSISSIPPI REBELS Sunshine Slam | W 67-63 | 2-1 | P. Flint 13 | P. Flint 2 | D. Meeks 8 |
| November 20, 2027 | #18 IOWA STATE CYCLONES Sunshine Slam | W 71-64 | 3-1 | P. Flint 29 | F. Howard 10 | D. Meeks 16 |
| November 22, 2027 | @ #24 Michigan State Spartans | L 61-68 | 3-2 | K. Johnson 10 | F. Howard 5 | K. Johnson 6 |
| November 25, 2027 | MILWAUKEE PANTHERS | L 63-66 | 3-3 | P. Flint 24 | P. Flint 6 | D. Meeks 9 |
| November 29, 2027 | UC-IRVINE ANTEATERS | W 80-66 | 4-3 | P. Flint 22 | F. Howard 6 | D. Meeks 9 |
| December 2, 2027 | @ #10 Gonzaga Bulldogs | L 52-69 | 4-4 | F. Howard 11 | T. Wallace 4 | D. Meeks 9 |
| December 6, 2027 | #23 MINNESOTA GOLDEN GOPHERS | W 77-67 | 5-4 | F. Howard 14 | F. Howard 3 | D. Meeks 14 |
| December 13, 2027 | @ Southern California Trojans | W 92-86 | 6-4 | K. Johnson 23 | F. Howard 9 | D. Meeks 9 |
| December 19, 2027 | RICHMOND SPIDERS | W 75-58 | 7-4 | P. Flint 23 | F. Howard 10 | K. Johnson 7 |
| December 26, 2027 | PROVIDENCE FRIARS* | W 71-60 | 8-4 | P. Flint 17 | K. Johnson 5 | K. Johnson 5 |
| December 30, 2027 | @ DePaul Blue Demons* | W 81-77 | 9-4 | F. Howard 16 | F. Howard 4 | D. Meeks 9 |
| January 2, 2028 | SETON HALL PIRATES* | W 75-60 | 10-4 | P. Flint 23 | P. Flint 6 | D. Meeks 12 |
| January 4, 2028 | CONNECTICUT HUSKIES* | W 70-63 | 11-4 | F. Howard 17 | P. Flint 6 | D. Meeks 11 |
| January 6, 2028 | @ Georgetown Hoyas* | L 69-73 | 11-5 | P. Flint 22 | F. Howard 9 | D. Meeks 11 |
| January 11, 2028 | @ #1 Marquette Golden Eagles* | L 60-89 | 11-6 | K. Johnson 14 | F. Howard 5 | D. Meeks 9 |
| January 16, 2028 | @ #18 Creighton Blue Jays* | W 82-67 | 12-6 | P. Flint 19 | F. Howard 8 | K. Johnson 11 |
| January 18, 2028 | ST. JOHNS RED STORM* | W 73-54 | 13-6 | D. Meeks 21 | P. Flint 7 | D. Meeks 8 |
| January 20, 2028 | #21 VILLANOVA WILDCATS* | L 74-82 | 13-7 | P. Flint 24 | K. Johnson 4 | D. Meeks 8 |
| January 25, 2028 | @ Xavier Musketeers* | L 60-75 | 13-8 | P. Flint 15 | F. Howard 5 | D. Meeks 9 |
| January 27, 2028 | @ Connecticut Huskies* | L 60-66 | 13-9 | P. Flint 13 | F. Howard 6 | B. Lostetter 9 |
| February 1, 2028 | GEORGETOWN HOYAS* | W 72-61 | 14-9 | D. Meeks 19 | F. Howard 5 | D. Meeks 21 |
| February 3, 2028 | DEPAUL BLUE DEMONS* | W 67-60 | 15-9 | D. Meeks 17 | F. Howard 5 | D. Meeks 14 |
| February 8, 2028 | @ Villanova Wildcats* | W 73-63 | 16-9 | D. Meeks 14 | F. Howard 6 | I. Cunningham 11 |
| February 10, 2028 | @ St. Johns Red Storm* | L 72-78 | 16-10 | P. Flint 23 | P. Flint 4 | D. Meeks 13 |
| February 17, 2028 | XAVIER MUSKETEERS* | W 69-54 | 17-10 | P. Flint 22 | P. Flint 7 | D. Meeks 11 |
| February 24, 2028 | CREIGHTON BLUE JAYS* | W 79-76 | 18-10 | P. Flint 20 | F. Howard 6 | D. Meeks 7 |
| February 27, 2028 | #1 MARQUETTE GOLDEN EAGLES* | L 59-71 | 18-11 | P. Flint 16 | P. Flint 6 | B. Lostetter 8 |
| March 1, 2028 | @ Providence Friars* | L 80-86 | 18-12 | P. Flint 29 | F. Howard 6 | K. Johnson 6 |
| March 3, 2028 | @ Seton Hall Pirates* | L 64-77 | 18-13 | D. Meeks 17 | F. Howard 4 | K. Johnson 9 |
| March 10, 2028 | XAVIER MUSKETEERS Big East Tournament | L 64-75 OT | 18-14 | P. Flint 28 | F. Howard 11 | K. Johnson 6 |
