| November 14, 2027 | @ Chattanooga Mocs | L 69-78 | 0-1 | D. Yeager 15 | M. Allen 3 | B. Kelly 8 |
| November 17, 2027 | BINGHAMTON BEARCATS | L 67-81 | 0-2 | D. Yeager 19 | M. Allen 6 | M. Lyons 7 |
| November 21, 2027 | SAN DIEGO TOREROS Hall of Fame Classic | L 79-95 | 0-3 | D. Yeager 15 | M. Allen 6 | T. Cundiff 7 |
| November 26, 2027 | @ Northern Colorado Bears | L 52-65 | 0-4 | M. Lyons 16 | D. Yeager 3 | T. Cundiff 5 |
| November 28, 2027 | @ Presbyterian Blue Hose | L 60-74 | 0-5 | B. Kelly 16 | M. Allen 6 | T. Cundiff 10 |
| December 1, 2027 | @ Purdue-Fort Wayne Mastodons | L 65-81 | 0-6 | T. Cundiff 13 | M. Allen 4 | M. Lyons 7 |
| December 5, 2027 | @ Alabama Crimson Tide | L 42-78 | 0-7 | G. Tracy 11 | D. Yeager 2 | M. Allen 5 |
| December 13, 2027 | @ Yale Bulldogs | W 68-65 OT | 1-7 | M. Allen 20 | B. Kelly 3 | B. Kelly 8 |
| December 19, 2027 | @ Denver Pioneers (4-7, 3-3 Home) | - | | | | |
| December 26, 2027 | @ Miami (OH) RedHawks (4-4, 0-0, 2-0 Home)* | - | | | | |
| December 29, 2027 | @ Bowling Green State Falcons (4-4, 0-0, 3-0 Home)* | - | | | | |
| January 2, 2028 | @ Toledo Rockets (5-4, 0-0, 1-0 Home)* | - | | | | |
| January 5, 2028 | @ Kent State Golden Flashes (6-3, 0-0, 5-0 Home)* | - | | | | |
| January 9, 2028 | EASTERN MICHIGAN EAGLES (5-3, 0-0, 2-3 Away)* | - | | | | |
| January 12, 2028 | OHIO BOBCATS (4-4, 0-0, 2-3 Away)* | - | | | | |
| January 16, 2028 | BALL STATE CARDINALS (2-5, 0-0, 1-4 Away)* | - | | | | |
| January 19, 2028 | @ Akron Zips (5-2, 0-0, 5-0 Home)* | - | | | | |
| January 23, 2028 | @ Western Michigan Broncos (2-6, 0-0, 2-0 Home)* | - | | | | |
| January 26, 2028 | CENTRAL MICHIGAN CHIPPEWAS (4-4, 0-0, 2-4 Away)* | - | | | | |
| January 30, 2028 | AKRON ZIPS (5-2, 0-0, 0-1 Away)* | - | | | | |
| February 2, 2028 | WESTERN MICHIGAN BRONCOS (2-6, 0-0, 0-5 Away)* | - | | | | |
| February 6, 2028 | @ Ohio Bobcats (4-4, 0-0, 2-0 Home)* | - | | | | |
| February 9, 2028 | @ Ball State Cardinals (2-5, 0-0, 1-1 Home)* | - | | | | |
| February 13, 2028 | TOLEDO ROCKETS (5-4, 0-0, 3-3 Away)* | - | | | | |
| February 16, 2028 | KENT STATE GOLDEN FLASHES (6-3, 0-0, 0-2 Away)* | - | | | | |
| February 20, 2028 | MIAMI (OH) REDHAWKS (4-4, 0-0, 2-4 Away)* | - | | | | |
| February 23, 2028 | @ Central Michigan Chippewas (4-4, 0-0, 2-0 Home)* | - | | | | |
| February 27, 2028 | BOWLING GREEN STATE FALCONS (4-4, 0-0, 1-4 Away)* | - | | | | |
| March 2, 2028 | @ Northern Illinois Huskies (5-2, 0-0, 3-0 Home)* | - | | | | |
