| November 13, 2027 | @ Mississippi State Bulldogs | L 50-74 | 0-1 | S. Reeder 11 | M. Tucker 3 | M. Tucker 7 |
| November 16, 2027 | SIU EDWARDSVILLE COUGARS | L 71-88 | 0-2 | S. Reeder 18 | G. Cotton 7 | S. Reeder 6 |
| November 19, 2027 | @ #24 Marquette Golden Eagles | L 49-71 | 0-3 | M. Tucker 12 | G. Cotton 2 | L. Harriman 6 |
| November 23, 2027 | @ Bowling Green State Falcons | L 73-89 | 0-4 | C. McIntyre 15 | G. Cotton 7 | M. Tucker 8 |
| November 26, 2027 | @ South Alabama Jaguars | L 65-79 | 0-5 | M. Tucker 16 | C. McIntyre 2 | C. McIntyre 6 |
| November 29, 2027 | CHARLESTON SOUTHERN BUCCANEERS | L 64-66 | 0-6 | C. McIntyre 16 | G. Cotton 3 | S. Reeder 8 |
| December 3, 2027 | SOUTH FLORIDA BULLS | W 80-68 | 1-6 | G. Cotton 13 | G. Cotton 7 | L. Harriman 9 |
| December 6, 2027 | GEORGE WASHINGTON REVOLUTIONARIES | L 59-75 | 1-7 | C. McIntyre 12 | B. Wilson 3 | C. McIntyre 6 |
| December 10, 2027 | MARIST RED FOXES | W 69-64 | 2-7 | G. Cotton 13 | G. Cotton 4 | S. Reeder 11 |
| December 13, 2027 | DETROIT MERCY TITANS | W 92-79 | 3-7 | C. McIntyre 20 | G. Cotton 8 | S. Reeder 8 |
| December 17, 2027 | @ Grambling Tigers | W 93-71 | 4-7 | C. McIntyre 23 | C. McIntyre 5 | C. McIntyre 5 |
| December 21, 2027 | @ San Diego State Aztecs | L 43-63 | 4-8 | L. Harriman 9 | G. Cotton 3 | S. Reeder 11 |
| December 24, 2027 | SACRED HEART PIONEERS | L 91-92 | 4-9 | C. McIntyre 16 | G. Cotton 4 | L. Harriman 4 |
| December 26, 2027 | IDAHO STATE BENGALS | L 74-87 | 4-10 | E. Callahan 14 | G. Cotton 5 | S. Reeder 11 |
| December 31, 2027 | LOYOLA (MD) GREYHOUNDS | L 58-76 | 4-11 | E. Marsh 14 | E. Marsh 4 | L. Harriman 7 |
| January 11, 2028 | YALE BULLDOGS* | L 58-72 | 4-12 | G. Cotton 23 | G. Cotton 2 | M. Tucker 8 |
| January 14, 2028 | @ Dartmouth Big Green* | W 80-71 OT | 5-12 | C. McIntyre 17 | G. Cotton 7 | M. Tucker 14 |
| January 18, 2028 | COLUMBIA LIONS* | W 69-64 | 6-12 | C. McIntyre 10 | G. Cotton 3 | E. Callahan 9 |
| January 21, 2028 | @ Harvard Crimson* | L 78-95 | 6-13 | C. McIntyre 19 | G. Cotton 3 | L. Harriman 7 |
| January 25, 2028 | @ Princeton Tigers* | W 68-61 | 7-13 | C. McIntyre 14 | G. Cotton 5 | M. Tucker 9 |
| January 28, 2028 | CORNELL BIG RED* | W 84-75 | 8-13 | M. Tucker 28 | C. McIntyre 8 | S. Reeder 7 |
| February 1, 2028 | @ Pennsylvania Quakers* | L 78-94 | 8-14 | C. McIntyre 22 | G. Cotton 4 | M. Tucker 4 |
| February 4, 2028 | @ Yale Bulldogs* | L 62-77 | 8-15 | C. McIntyre 19 | L. Harriman 5 | S. Reeder 7 |
| February 8, 2028 | DARTMOUTH BIG GREEN* | L 73-81 | 8-16 | M. Tucker 24 | M. Tucker 4 | L. Harriman 6 |
| February 11, 2028 | @ Columbia Lions* | W 75-61 | 9-16 | C. McIntyre 23 | G. Cotton 8 | C. McIntyre 6 |
| February 15, 2028 | HARVARD CRIMSON* | L 57-61 OT | 9-17 | M. Tucker 11 | L. Harriman 4 | M. Tucker 14 |
| February 18, 2028 | PRINCETON TIGERS* | W 82-74 | 10-17 | M. Tucker 19 | G. Cotton 8 | M. Tucker 8 |
| February 22, 2028 | @ Cornell Big Red* | L 64-75 | 10-18 | M. Tucker 17 | G. Cotton 4 | S. Reeder 12 |
| February 25, 2028 | PENNSYLVANIA QUAKERS* | W 78-67 | 11-18 | C. McIntyre 21 | M. Tucker 6 | M. Tucker 11 |
