| November 14, 2027 | LONGWOOD LANCERS | L 85-88 | 0-1 | B. Lowe 21 | B. Lowe 10 | K. Clay 5 |
| November 21, 2027 | SAN JOSE STATE SPARTANS Hall of Fame Classic | L 52-71 | 0-2 | A. Harvey 12 | B. Lowe 2 | K. Cheeks 6 |
| November 25, 2027 | OHIO STATE BUCKEYES | L 74-76 | 0-3 | A. Harvey 25 | B. Lowe 6 | W. Rolle 8 |
| November 29, 2027 | XAVIER MUSKETEERS | L 72-81 | 0-4 | A. Harvey 18 | B. Lowe 14 | K. Taylor 9 |
| December 1, 2027 | CLEVELAND STATE VIKINGS | W 86-76 | 1-4 | B. Lowe 16 | B. Lowe 6 | W. Rolle 5 |
| December 6, 2027 | PENNSYLVANIA QUAKERS | W 88-73 | 2-4 | B. Lowe 25 | T. Hobbs 7 | K. Taylor 10 |
| December 13, 2027 | SOUTH DAKOTA COYOTES | L 62-73 | 2-5 | B. Lowe 13 | K. Caldwell 4 | K. Clay 10 |
| December 17, 2027 | MISSISSIPPI REBELS | W 96-81 | 3-5 | K. Taylor 17 | B. Lowe 6 | K. Taylor 8 |
| December 20, 2027 | @ #25 Michigan State Spartans | W 74-71 | 4-5 | B. Lowe 25 | B. Lowe 4 | K. Caldwell 4 |
| December 28, 2027 | #4 WEST VIRGINIA MOUNTAINEERS* | W 92-86 | 5-5 | B. Lowe 23 | B. Lowe 7 | K. Clay 7 |
| January 2, 2028 | @ #8 Arizona Wildcats* | L 80-93 | 5-6 | K. Caldwell 14 | B. Lowe 8 | K. Taylor 5 |
| January 4, 2028 | #13 OKLAHOMA STATE COWBOYS* | L 55-79 | 5-7 | K. Taylor 10 | B. Lowe 3 | K. Caldwell 7 |
| January 6, 2028 | @ Texas Tech Red Raiders* | L 68-81 | 5-8 | J. Bonner 16 | B. Lowe 6 | K. Taylor 6 |
| January 11, 2028 | @ Kansas State Wildcats* | L 78-85 OT | 5-9 | B. Lowe 25 | B. Lowe 4 | K. Cheeks 8 |
| January 13, 2028 | #25 BRIGHAM YOUNG COUGARS* | L 53-69 | 5-10 | A. Harvey 19 | B. Lowe 7 | K. Cheeks 8 |
| January 18, 2028 | @ Iowa State Cyclones* | L 76-94 | 5-11 | K. Taylor 21 | B. Lowe 5 | A. Harvey 8 |
| January 20, 2028 | #3 KANSAS JAYHAWKS* | W 89-78 OT | 6-11 | K. Clay 17 | B. Lowe 7 | K. Caldwell 7 |
| January 25, 2028 | #7 ARIZONA WILDCATS* | L 65-72 | 6-12 | B. Lowe 15 | B. Lowe 8 | K. Taylor 13 |
| January 27, 2028 | @ Baylor Bears* | L 57-77 | 6-13 | B. Lowe 13 | K. Taylor 4 | K. Taylor 6 |
| January 30, 2028 | KANSAS STATE WILDCATS* | W 84-74 | 7-13 | K. Clay 18 | B. Lowe 7 | K. Caldwell 10 |
| February 3, 2028 | @ #21 Brigham Young Cougars* | L 73-91 | 7-14 | A. Harvey 14 | B. Lowe 2 | K. Taylor 10 |
| February 8, 2028 | COLORADO BUFFALOES* | W 92-71 | 8-14 | K. Clay 16 | B. Lowe 10 | K. Taylor 7 |
| February 10, 2028 | @ Texas Christian Horned Frogs* | L 76-92 | 8-15 | J. Bonner 16 | B. Lowe 10 | A. Harvey 6 |
| February 15, 2028 | @ Houston Cougars* | W 83-76 | 9-15 | A. Harvey 25 | T. Hobbs 5 | K. Clay 6 |
| February 17, 2028 | UTAH UTES* | W 76-72 | 10-15 | B. Lowe 16 | B. Lowe 8 | K. Clay 7 |
| February 20, 2028 | @ Colorado Buffaloes* | W 82-72 | 11-15 | B. Lowe 22 | B. Lowe 6 | K. Clay 7 |
| February 24, 2028 | CENTRAL FLORIDA KNIGHTS* | L 71-90 | 11-16 | K. Clay 20 | B. Lowe 4 | K. Taylor 6 |
| February 27, 2028 | @ #5 Kansas Jayhawks* | L 63-77 | 11-17 | B. Lowe 19 | B. Lowe 2 | K. Caldwell 9 |
| March 3, 2028 | #13 CINCINNATI BEARCATS* | W 87-84 OT | 12-17 | B. Lowe 20 | A. Harvey 8 | K. Taylor 12 |
| March 8, 2028 | TEXAS CHRISTIAN HORNED FROGS Big 12 Tournament | W 87-81 | 13-17 | B. Lowe 22 | B. Lowe 6 | A. Harvey 6 |
| March 9, 2028 | @ #19 Oklahoma State Cowboys Big 12 Tournament | L 55-91 | 13-18 | K. Taylor 10 | B. Lowe 8 | K. Taylor 7 |
