| November 15, 2027 | SOUTHERN UTAH THUNDERBIRDS | W 71-56 | 1-0 | G. Wilkins 18 | C. Blossom 6 | T. Dobbins 10 |
| November 17, 2027 | @ Oregon State Beavers | W 88-79 | 2-0 | A. Powell 13 | C. Blossom 8 | D. Haskins 14 |
| November 21, 2027 | EASTERN KENTUCKY COLONELS | W 86-74 | 3-0 | T. Dobbins 20 | C. Blossom 6 | K. Thompkins 10 |
| November 25, 2027 | ST. THOMAS TOMMIES Paradise Jam | L 68-77 | 3-1 | W. Battle 11 | C. Blossom 6 | T. Dobbins 7 |
| November 29, 2027 | @ Texas Longhorns | W 90-82 | 4-1 | C. Blossom 21 | C. Blossom 10 | T. Dobbins 13 |
| December 2, 2027 | RADFORD HIGHLANDERS | W 80-62 | 5-1 | T. Barrett 14 | C. Blossom 8 | T. Dobbins 9 |
| December 9, 2027 | AKRON ZIPS | W 85-61 | 6-1 | T. Dobbins 21 | G. Wilkins 5 | W. Battle 8 |
| December 17, 2027 | ORAL ROBERTS GOLDEN EAGLES | L 81-97 | 6-2 | W. Battle 18 | C. Blossom 8 | W. Battle 7 |
| December 22, 2027 | NORFOLK STATE SPARTANS | W 93-59 | 7-2 | W. Battle 22 | C. Blossom 7 | D. Haskins 11 |
| December 28, 2027 | COLORADO BUFFALOES* | L 79-87 | 7-3 | W. Battle 20 | A. Powell 6 | T. Dobbins 6 |
| December 30, 2027 | @ Utah Utes* | L 78-84 OT | 7-4 | G. Wilkins 25 | C. Blossom 3 | T. Dobbins 8 |
| January 4, 2028 | @ West Virginia Mountaineers* | L 78-85 | 7-5 | W. Battle 19 | C. Blossom 8 | K. Thompkins 9 |
| January 6, 2028 | #18 HOUSTON COUGARS* | W 76-67 | 8-5 | C. Blossom 13 | C. Blossom 6 | T. Dobbins 11 |
| January 9, 2028 | @ #11 Iowa State Cyclones* | L 91-99 | 8-6 | T. Dobbins 17 | D. Haskins 6 | T. Dobbins 10 |
| January 13, 2028 | #25 ARIZONA WILDCATS* | L 68-78 | 8-7 | D. Woodruff 22 | C. Blossom 6 | K. Thompkins 6 |
| January 18, 2028 | @ Kansas State Wildcats* | L 71-89 | 8-8 | G. Wilkins 17 | C. Blossom 9 | T. Dobbins 10 |
| January 23, 2028 | TEXAS TECH RED RAIDERS* | W 81-64 | 9-8 | C. Blossom 14 | C. Blossom 10 | T. Dobbins 17 |
| January 25, 2028 | #2 KANSAS JAYHAWKS* | L 70-71 | 9-9 | G. Wilkins 16 | C. Blossom 6 | T. Dobbins 6 |
| January 27, 2028 | @ Texas Christian Horned Frogs* | L 73-91 | 9-10 | C. Blossom 11 | D. Haskins 5 | K. Thompkins 5 |
| February 1, 2028 | BAYLOR BEARS* | L 68-79 | 9-11 | T. Dobbins 13 | C. Blossom 5 | W. Battle 6 |
| February 3, 2028 | @ #17 Arizona Wildcats* | L 66-81 | 9-12 | W. Battle 17 | C. Blossom 4 | D. Haskins 10 |
| February 8, 2028 | #3 BRIGHAM YOUNG COUGARS* | L 92-96 | 9-13 | C. Blossom 22 | A. Powell 5 | T. Barrett 5 |
| February 10, 2028 | @ Texas Tech Red Raiders* | W 82-67 | 10-13 | G. Wilkins 18 | G. Wilkins 5 | D. Haskins 9 |
| February 15, 2028 | @ #5 Kansas Jayhawks* | L 57-84 | 10-14 | W. Battle 20 | C. Blossom 3 | T. Dobbins 7 |
| February 17, 2028 | CENTRAL FLORIDA KNIGHTS* | W 78-68 | 11-14 | C. Blossom 14 | C. Blossom 5 | T. Dobbins 7 |
| February 20, 2028 | TEXAS CHRISTIAN HORNED FROGS* | L 70-74 | 11-15 | T. Dobbins 14 | T. Dobbins 4 | T. Dobbins 8 |
| February 24, 2028 | @ Cincinnati Bearcats* | W 101-89 | 12-15 | G. Wilkins 20 | C. Blossom 6 | W. Battle 8 |
| March 1, 2028 | OKLAHOMA STATE COWBOYS* | W 79-65 | 13-15 | T. Dobbins 14 | C. Blossom 5 | T. Dobbins 9 |
| March 3, 2028 | @ #3 Brigham Young Cougars* | L 74-75 | 13-16 | C. Blossom 20 | C. Blossom 5 | K. Thompkins 10 |
| March 8, 2028 | @ Utah Utes (14-17, 9-9 Home) Big 12 Tournament | - | | | | |
