| November 14, 2027 | RADFORD HIGHLANDERS | W 82-75 | 1-0 | E. Forman 18 | B. Blackmon 7 | F. Ledesma 12 |
| November 17, 2027 | UC-RIVERSIDE HIGHLANDERS | W 83-70 | 2-0 | A. Worley 22 | B. Blackmon 6 | L. Irvin 10 |
| November 23, 2027 | @ Stetson Hatters | L 84-85 | 2-1 | F. Ledesma 20 | B. Blackmon 3 | L. Irvin 15 |
| November 25, 2027 | @ #4 Virginia Cavaliers | L 61-75 | 2-2 | E. Forman 18 | B. Blackmon 7 | L. Irvin 8 |
| November 28, 2027 | @ Green Bay Phoenix | L 75-88 | 2-3 | F. Ledesma 19 | B. Blackmon 9 | L. Irvin 7 |
| December 3, 2027 | @ South Carolina Gamecocks | L 59-82 | 2-4 | A. Worley 13 | B. Blackmon 6 | L. Irvin 11 |
| December 6, 2027 | @ Southern California Trojans | L 53-73 | 2-5 | L. Irvin 14 | B. Blackmon 4 | L. Irvin 12 |
| December 8, 2027 | WESTERN MICHIGAN BRONCOS | W 73-56 | 3-5 | F. Ledesma 19 | B. Blackmon 5 | F. Ledesma 14 |
| December 13, 2027 | @ Nevada-Las Vegas Runnin' Rebels | L 72-92 | 3-6 | A. Worley 20 | E. Forman 5 | F. Ledesma 8 |
| December 20, 2027 | @ DePaul Blue Demons | L 67-97 | 3-7 | D. McCaffery 12 | M. Besecker 3 | L. Irvin 10 |
| December 28, 2027 | @ Austin Peay Governors | W 85-66 | 4-7 | A. Worley 19 | B. Blackmon 5 | A. Worley 6 |
| January 4, 2028 | @ American Eagles* | L 89-99 | 4-8 | A. Worley 22 | B. Blackmon 8 | F. Ledesma 8 |
| January 7, 2028 | LAFAYETTE LEOPARDS* | W 90-73 | 5-8 | A. Worley 27 | B. Blackmon 11 | F. Ledesma 9 |
| January 11, 2028 | LEHIGH MOUNTAIN HAWKS* | L 90-100 | 5-9 | E. Forman 20 | B. Blackmon 2 | F. Ledesma 7 |
| January 14, 2028 | @ Loyola (MD) Greyhounds* | L 71-82 | 5-10 | E. Forman 14 | B. Blackmon 5 | F. Ledesma 7 |
| January 18, 2028 | COLGATE RAIDERS* | W 64-62 | 6-10 | L. Irvin 14 | B. Blackmon 6 | L. Sampson 7 |
| January 21, 2028 | @ Holy Cross Crusaders* | L 59-75 | 6-11 | L. Sampson 17 | A. Worley 3 | L. Irvin 10 |
| January 25, 2028 | BUCKNELL BISON* | W 75-58 | 7-11 | L. Irvin 15 | E. Forman 4 | L. Irvin 12 |
| January 28, 2028 | @ Boston University Terriers* | W 91-68 | 8-11 | F. Ledesma 26 | B. Blackmon 10 | F. Ledesma 8 |
| February 1, 2028 | NAVY MIDSHIPMEN* | W 92-68 | 9-11 | F. Ledesma 24 | S. Scott 4 | F. Ledesma 10 |
| February 4, 2028 | AMERICAN EAGLES* | L 80-97 | 9-12 | E. Forman 17 | B. Blackmon 7 | L. Sampson 7 |
| February 8, 2028 | @ Lafayette Leopards* | L 75-92 | 9-13 | A. Worley 21 | B. Blackmon 8 | F. Ledesma 5 |
| February 11, 2028 | @ Lehigh Mountain Hawks* | L 76-82 | 9-14 | A. Worley 21 | B. Blackmon 6 | F. Ledesma 10 |
| February 15, 2028 | LOYOLA (MD) GREYHOUNDS* | W 81-75 | 10-14 | E. Forman 13 | B. Blackmon 3 | E. Forman 5 |
| February 18, 2028 | @ Colgate Raiders* | L 63-82 | 10-15 | A. Worley 19 | E. Forman 5 | L. Irvin 10 |
| February 22, 2028 | HOLY CROSS CRUSADERS* | W 77-55 | 11-15 | F. Ledesma 14 | B. Blackmon 4 | F. Ledesma 10 |
| February 25, 2028 | @ Bucknell Bison* | L 61-79 | 11-16 | F. Ledesma 13 | B. Blackmon 2 | F. Ledesma 9 |
| March 1, 2028 | BOSTON UNIVERSITY TERRIERS* | W 83-72 | 12-16 | E. Forman 23 | A. Worley 4 | F. Ledesma 9 |
| March 4, 2028 | @ Navy Midshipmen* | L 66-76 | 12-17 | F. Ledesma 17 | B. Blackmon 9 | F. Ledesma 9 |
| March 6, 2028 | BOSTON UNIVERSITY TERRIERS Patriot Tournament | W 96-81 | 13-17 | A. Worley 22 | B. Blackmon 4 | L. Irvin 8 |
| March 7, 2028 | @ Lafayette Leopards Patriot Tournament | W 83-78 | 14-17 | A. Worley 18 | B. Blackmon 8 | L. Irvin 9 |
| March 8, 2028 | NAVY MIDSHIPMEN Patriot Tournament | L 85-91 | 14-18 | A. Worley 19 | B. Blackmon 9 | L. Sampson 9 |
