| November 14, 2027 | RADFORD HIGHLANDERS | W 82-75 | 1-0 | E. Forman 18 | B. Blackmon 7 | F. Ledesma 12 |
| November 17, 2027 | UC-RIVERSIDE HIGHLANDERS | W 83-70 | 2-0 | A. Worley 22 | B. Blackmon 6 | L. Irvin 10 |
| November 23, 2027 | @ Stetson Hatters | L 84-85 | 2-1 | F. Ledesma 20 | B. Blackmon 3 | L. Irvin 15 |
| November 25, 2027 | @ #4 Virginia Cavaliers | L 61-75 | 2-2 | E. Forman 18 | B. Blackmon 7 | L. Irvin 8 |
| November 28, 2027 | @ Green Bay Phoenix | L 75-88 | 2-3 | F. Ledesma 19 | B. Blackmon 9 | L. Irvin 7 |
| December 3, 2027 | @ South Carolina Gamecocks | L 59-82 | 2-4 | A. Worley 13 | B. Blackmon 6 | L. Irvin 11 |
| December 6, 2027 | @ Southern California Trojans | L 53-73 | 2-5 | L. Irvin 14 | B. Blackmon 4 | L. Irvin 12 |
| December 8, 2027 | WESTERN MICHIGAN BRONCOS | W 73-56 | 3-5 | F. Ledesma 19 | B. Blackmon 5 | F. Ledesma 14 |
| December 13, 2027 | @ Nevada-Las Vegas Runnin' Rebels | L 72-92 | 3-6 | A. Worley 20 | E. Forman 5 | F. Ledesma 8 |
| December 20, 2027 | @ DePaul Blue Demons (6-2, 5-0 Home) | - | | | | |
| December 28, 2027 | @ Austin Peay Governors (2-8, 1-2 Home) | - | | | | |
| January 4, 2028 | @ American Eagles (5-4, 0-0, 3-0 Home)* | - | | | | |
| January 7, 2028 | LAFAYETTE LEOPARDS (2-6, 0-0, 1-4 Away)* | - | | | | |
| January 11, 2028 | LEHIGH MOUNTAIN HAWKS (5-4, 0-0, 0-2 Away)* | - | | | | |
| January 14, 2028 | @ Loyola (MD) Greyhounds (4-4, 0-0, 2-1 Home)* | - | | | | |
| January 18, 2028 | COLGATE RAIDERS (7-2, 0-0, 4-1 Away)* | - | | | | |
| January 21, 2028 | @ Holy Cross Crusaders (5-3, 0-0, 4-3 Home)* | - | | | | |
| January 25, 2028 | BUCKNELL BISON (2-5, 0-0, 1-4 Away)* | - | | | | |
| January 28, 2028 | @ Boston University Terriers (4-5, 0-0, 3-0 Home)* | - | | | | |
| February 1, 2028 | NAVY MIDSHIPMEN (3-6, 0-0, 1-5 Away)* | - | | | | |
| February 4, 2028 | AMERICAN EAGLES (5-4, 0-0, 2-4 Away)* | - | | | | |
| February 8, 2028 | @ Lafayette Leopards (2-6, 0-0, 1-2 Home)* | - | | | | |
| February 11, 2028 | @ Lehigh Mountain Hawks (5-4, 0-0, 5-2 Home)* | - | | | | |
| February 15, 2028 | LOYOLA (MD) GREYHOUNDS (4-4, 0-0, 2-3 Away)* | - | | | | |
| February 18, 2028 | @ Colgate Raiders (7-2, 0-0, 3-1 Home)* | - | | | | |
| February 22, 2028 | HOLY CROSS CRUSADERS (5-3, 0-0, 1-0 Away)* | - | | | | |
| February 25, 2028 | @ Bucknell Bison (2-5, 0-0, 1-0 Home)* | - | | | | |
| March 1, 2028 | BOSTON UNIVERSITY TERRIERS (4-5, 0-0, 1-4 Away)* | - | | | | |
| March 4, 2028 | @ Navy Midshipmen (3-6, 0-0, 2-1 Home)* | - | | | | |
