| November 21, 2025 | ST. THOMAS TOMMIES Charleston Classic | W 80-75 | 1-0 | M. Coffee 23 | T. Clemmons 7 | T. Melson 10 |
| November 22, 2025 | @ Toledo Rockets Charleston Classic | W 94-53 | 2-0 | T. Melson 26 | T. Clemmons 6 | K. Higgins 12 |
| November 23, 2025 | @ Creighton Blue Jays Charleston Classic | L 105-112 OT | 2-1 | T. Melson 29 | T. Clemmons 9 | G. McKamey 9 |
| November 25, 2025 | NIAGARA PURPLE EAGLES | W 89-47 | 3-1 | T. Clemmons 17 | T. Clemmons 4 | K. Higgins 11 |
| November 28, 2025 | PENN STATE NITTANY LIONS | W 84-73 | 4-1 | T. Clemmons 28 | K. Higgins 5 | K. Higgins 8 |
| December 3, 2025 | BALL STATE CARDINALS | W 90-63 | 5-1 | T. Melson 26 | T. Clemmons 10 | G. McKamey 10 |
| December 6, 2025 | MARIST RED FOXES | W 74-45 | 6-1 | T. Melson 24 | T. Clemmons 7 | K. Higgins 13 |
| December 9, 2025 | NORTHERN COLORADO BEARS | W 82-62 | 7-1 | T. Melson 20 | T. Clemmons 8 | T. Clemmons 8 |
| December 12, 2025 | OMAHA MAVERICKS | W 90-71 | 8-1 | G. McKamey 22 | L. Smith 3 | G. McKamey 9 |
| December 17, 2025 | SO. CAROLINA UPSTATE SPARTANS | W 77-55 | 9-1 | T. Melson 19 | T. Clemmons 8 | G. McKamey 7 |
| December 23, 2025 | QUINNIPIAC BOBCATS | W 90-63 | 10-1 | T. Melson 22 | T. Clemmons 7 | L. Smith 10 |
| December 26, 2025 | @ Clemson Tigers* | W 71-64 | 11-1 | T. Melson 19 | T. Clemmons 3 | G. McKamey 12 |
| December 28, 2025 | @ Georgia Tech Yellow Jackets* | W 73-64 | 12-1 | T. Melson 27 | T. Clemmons 5 | K. Higgins 10 |
| January 2, 2026 | LOUISVILLE CARDINALS* | W 91-83 | 13-1 | T. Clemmons 19 | T. Melson 4 | G. McKamey 8 |
| January 4, 2026 | @ Virginia Cavaliers* | L 83-105 | 13-2 | T. Clemmons 23 | T. Clemmons 6 | K. Higgins 10 |
| January 9, 2026 | CALIFORNIA GOLDEN BEARS* | W 76-56 | 14-2 | T. Clemmons 20 | K. Higgins 4 | K. Higgins 14 |
| January 11, 2026 | @ #1 Duke Blue Devils* | L 83-93 | 14-3 | T. Clemmons 23 | T. Clemmons 7 | M. Coffee 10 |
| January 16, 2026 | MIAMI (FL) HURRICANES* | W 75-73 | 15-3 | T. Clemmons 18 | T. Clemmons 5 | T. Melson 12 |
| January 18, 2026 | @ Syracuse Orange* | W 90-77 | 16-3 | T. Clemmons 23 | T. Melson 6 | K. Higgins 8 |
| January 23, 2026 | BOSTON COLLEGE EAGLES* | W 94-78 | 17-3 | G. McKamey 27 | T. Clemmons 7 | G. McKamey 9 |
| January 25, 2026 | VIRGINIA TECH HOKIES* | W 87-79 | 18-3 | M. Coffee 27 | T. Clemmons 5 | T. Melson 8 |
| January 30, 2026 | @ Florida State Seminoles* | W 79-69 | 19-3 | T. Melson 27 | T. Clemmons 5 | M. Coffee 9 |
| February 1, 2026 | STANFORD CARDINAL* | W 75-59 | 20-3 | T. Clemmons 20 | T. Clemmons 6 | M. Coffee 6 |
| February 6, 2026 | PITTSBURGH PANTHERS* | W 95-83 | 21-3 | K. Higgins 19 | T. Clemmons 7 | K. Higgins 13 |
| February 8, 2026 | @ Notre Dame Fighting Irish* | W 83-73 | 22-3 | T. Melson 25 | T. Clemmons 6 | T. Melson 10 |
| February 13, 2026 | #19 NORTH CAROLINA TAR HEELS* | W 85-69 | 23-3 | T. Melson 23 | T. Clemmons 9 | G. McKamey 13 |
| February 15, 2026 | @ NC-State Wolfpack* | L 70-74 | 23-4 | T. Melson 18 | T. Clemmons 7 | T. Clemmons 8 |
| February 20, 2026 | WAKE FOREST DEMON DEACONS* | W 87-75 | 24-4 | T. Melson 28 | T. Clemmons 5 | K. Higgins 15 |
| February 22, 2026 | NOTRE DAME FIGHTING IRISH* | W 88-72 | 25-4 | T. Melson 23 | T. Clemmons 5 | K. Higgins 12 |
| February 27, 2026 | @ #22 North Carolina Tar Heels* | L 66-84 | 25-5 | M. Coffee 14 | T. Clemmons 6 | M. Coffee 8 |
| March 1, 2026 | @ Louisville Cardinals* | W 81-70 | 26-5 | K. Higgins 25 | T. Clemmons 5 | K. Higgins 12 |
| March 10, 2026 | #23 NORTH CAROLINA TAR HEELS ACC Tournament | L 86-87 | 26-6 | T. Melson 23 | T. Clemmons 7 | M. Coffee 11 |
| March 17, 2026 | UCLA BRUINS NCAA Tournament | L 68-85 | 26-7 | T. Melson 15 | T. Clemmons 7 | G. McKamey 10 |
