| November 14, 2025 | @ #22 Texas A&M Aggies | L 53-75 | 0-1 | N. Brinker 10 | E. Barkley 2 | D. Webber 5 |
| November 17, 2025 | NORTH TEXAS MEAN GREEN | L 91-99 | 0-2 | G. Farmer 23 | E. Barkley 7 | N. Brinker 6 |
| November 21, 2025 | NORTH ALABAMA LIONS | W 77-51 | 1-2 | K. Stewart 20 | E. Barkley 5 | E. Barkley 7 |
| November 24, 2025 | APPALACHIAN STATE MOUNTAINEERS | W 78-68 | 2-2 | T. Jacobson 17 | Q. Holiday 5 | E. Barkley 6 |
| November 28, 2025 | @ Southern Methodist Mustangs | L 73-84 | 2-3 | C. Woolfolk 13 | T. Jacobson 4 | G. Farmer 9 |
| December 5, 2025 | OHIO BOBCATS | W 90-75 | 3-3 | E. Barkley 21 | E. Barkley 5 | S. Ammons 7 |
| December 8, 2025 | TARLETON STATE TEXANS | W 94-83 | 4-3 | E. Barkley 21 | E. Barkley 6 | G. Farmer 8 |
| December 12, 2025 | WYOMING COWBOYS | L 77-85 | 4-4 | G. Farmer 18 | Q. Holiday 4 | N. Brinker 7 |
| December 19, 2025 | TEXAS-EL PASO MINERS | L 81-92 | 4-5 | G. Farmer 14 | Q. Holiday 4 | D. Webber 6 |
| December 26, 2025 | @ #17 Minnesota Golden Gophers* | L 47-82 | 4-6 | G. Farmer 14 | E. Barkley 5 | E. Barkley 4 |
| December 28, 2025 | @ #21 Washington Huskies* | L 70-89 | 4-7 | T. Jacobson 11 | T. Jacobson 5 | E. Barkley 8 |
| January 2, 2026 | RUTGERS SCARLET KNIGHTS* | W 81-58 | 5-7 | G. Farmer 16 | Q. Holiday 4 | G. Farmer 9 |
| January 4, 2026 | @ Ohio State Buckeyes* | L 72-83 | 5-8 | K. Stewart 14 | N. Brinker 5 | D. Webber 5 |
| January 9, 2026 | @ Oregon Ducks* | L 54-71 | 5-9 | K. Stewart 11 | E. Barkley 4 | K. Stewart 5 |
| January 11, 2026 | NEBRASKA CORNHUSKERS* | L 78-83 | 5-10 | G. Farmer 29 | C. Woolfolk 4 | D. Webber 11 |
| January 16, 2026 | @ #7 Michigan State Spartans* | L 73-89 | 5-11 | Q. Holiday 12 | E. Barkley 6 | E. Barkley 6 |
| January 18, 2026 | @ #21 Iowa Hawkeyes* | L 59-81 | 5-12 | G. Farmer 15 | E. Barkley 3 | E. Barkley 4 |
| January 23, 2026 | @ Maryland Terrapins* | W 82-66 | 6-12 | G. Farmer 15 | E. Barkley 4 | G. Farmer 8 |
| January 25, 2026 | @ Indiana Hoosiers* | L 73-88 | 6-13 | K. Stewart 16 | E. Barkley 4 | E. Barkley 5 |
| January 30, 2026 | #3 PURDUE BOILERMAKERS* | L 57-86 | 6-14 | G. Farmer 15 | E. Barkley 2 | K. Stewart 8 |
| February 1, 2026 | #8 MICHIGAN WOLVERINES* | L 55-87 | 6-15 | E. Barkley 14 | E. Barkley 4 | D. Webber 6 |
| February 6, 2026 | NORTHWESTERN WILDCATS* | W 77-61 | 7-15 | G. Farmer 16 | E. Barkley 6 | Q. Holiday 5 |
| February 8, 2026 | @ #11 Illinois Fighting Illini* | L 80-105 | 7-16 | S. Ammons 23 | E. Barkley 4 | S. Ammons 7 |
| February 13, 2026 | WISCONSIN BADGERS* | L 67-89 | 7-17 | D. Webber 14 | T. Jacobson 8 | N. Brinker 5 |
| February 15, 2026 | SOUTHERN CALIFORNIA TROJANS* | L 56-66 | 7-18 | G. Farmer 19 | E. Barkley 3 | G. Farmer 11 |
| February 20, 2026 | @ UCLA Bruins* | L 72-84 | 7-19 | G. Farmer 14 | E. Barkley 5 | K. Stewart 5 |
| February 22, 2026 | MINNESOTA GOLDEN GOPHERS* | L 72-83 | 7-20 | G. Farmer 16 | E. Barkley 4 | Q. Holiday 6 |
| February 27, 2026 | INDIANA HOOSIERS* | L 67-85 | 7-21 | Q. Holiday 10 | E. Barkley 5 | G. Farmer 7 |
| March 1, 2026 | IOWA HAWKEYES* | W 76-64 | 8-21 | G. Farmer 19 | T. Jacobson 5 | K. Stewart 10 |
