| November 14, 2025 | INCARNATE WORD CARDINALS | W 70-52 | 1-0 | J. Brennan 20 | J. Brennan 6 | B. Nee 8 |
| November 17, 2025 | BUCKNELL BISON | W 81-47 | 2-0 | K. Mason 22 | A. Johnson 5 | K. Mason 15 |
| November 21, 2025 | VILLANOVA WILDCATS | W 90-69 | 3-0 | J. Brennan 30 | J. Brennan 6 | J. Simmons 8 |
| November 24, 2025 | SOUTH DAKOTA COYOTES | L 70-74 | 3-1 | J. Brennan 22 | J. Brennan 5 | J. Simmons 8 |
| November 28, 2025 | @ Cincinnati Bearcats | W 102-92 | 4-1 | J. Brennan 27 | A. Johnson 4 | B. Nee 8 |
| December 5, 2025 | PRAIRIE VIEW PANTHERS | W 81-64 | 5-1 | J. Brennan 27 | A. Johnson 4 | J. Simmons 5 |
| December 12, 2025 | NAVY MIDSHIPMEN | W 102-76 | 6-1 | E. Darby 25 | D. Williams 6 | K. Mason 15 |
| December 19, 2025 | SOUTHERN INDIANA SCREAMING EAGLES | W 85-67 | 7-1 | J. Brennan 16 | A. Johnson 6 | J. Simmons 15 |
| December 23, 2025 | @ Arkansas Razorbacks JAG Holiday Invitational | L 94-101 | 7-2 | J. Brennan 25 | J. Brennan 6 | A. Johnson 6 |
| December 26, 2025 | INDIANA HOOSIERS* | W 94-74 | 8-2 | E. Darby 26 | J. Brennan 7 | K. Mason 8 |
| December 28, 2025 | @ #5 Michigan State Spartans* | L 77-83 | 8-3 | E. Darby 18 | J. Brennan 6 | K. Mason 12 |
| January 2, 2026 | #24 ILLINOIS FIGHTING ILLINI* | L 91-104 | 8-4 | J. Brennan 23 | J. Brennan 7 | J. Simmons 7 |
| January 4, 2026 | @ #14 Iowa Hawkeyes* | L 85-98 | 8-5 | K. Mason 24 | A. Johnson 5 | A. Johnson 6 |
| January 9, 2026 | NORTHWESTERN WILDCATS* | W 99-85 | 9-5 | J. Brennan 35 | J. Brennan 5 | J. Brennan 5 |
| January 11, 2026 | @ Penn State Nittany Lions* | W 83-78 | 10-5 | A. Johnson 17 | J. Brennan 5 | A. Johnson 6 |
| January 16, 2026 | WISCONSIN BADGERS* | W 89-63 | 11-5 | J. Simmons 24 | J. Brennan 6 | K. Mason 9 |
| January 18, 2026 | @ Southern California Trojans* | W 71-64 | 12-5 | E. Darby 26 | A. Johnson 4 | J. Brennan 8 |
| January 23, 2026 | @ Rutgers Scarlet Knights* | W 105-85 | 13-5 | K. Mason 27 | J. Brennan 6 | K. Mason 8 |
| January 25, 2026 | @ #3 Purdue Boilermakers* | L 73-84 | 13-6 | K. Mason 16 | D. Williams 5 | K. Mason 15 |
| January 30, 2026 | @ Ohio State Buckeyes* | W 82-67 | 14-6 | J. Brennan 20 | J. Brennan 4 | K. Mason 11 |
| February 1, 2026 | #20 MINNESOTA GOLDEN GOPHERS* | W 83-69 | 15-6 | J. Brennan 22 | A. Johnson 5 | J. Simmons 11 |
| February 6, 2026 | #13 WASHINGTON HUSKIES* | W 91-82 | 16-6 | A. Johnson 15 | J. Brennan 7 | E. Darby 7 |
| February 8, 2026 | OREGON DUCKS* | W 97-85 | 17-6 | K. Mason 21 | J. Brennan 6 | J. Simmons 8 |
| February 13, 2026 | UCLA BRUINS* | W 103-69 | 18-6 | E. Darby 20 | J. Brennan 7 | K. Mason 10 |
| February 15, 2026 | @ #11 Michigan Wolverines* | W 99-84 | 19-6 | J. Brennan 34 | J. Brennan 7 | K. Mason 13 |
| February 20, 2026 | @ Maryland Terrapins* | L 63-78 | 19-7 | A. Johnson 17 | J. Brennan 3 | J. Simmons 11 |
| February 22, 2026 | @ Oregon Ducks* | W 100-76 | 20-7 | J. Brennan 25 | A. Johnson 6 | J. Simmons 6 |
| February 27, 2026 | #5 PURDUE BOILERMAKERS* | W 86-68 | 21-7 | J. Brennan 25 | A. Johnson 7 | K. Mason 15 |
| March 1, 2026 | #13 MICHIGAN WOLVERINES* | L 89-102 | 21-8 | J. Brennan 31 | J. Brennan 9 | J. Simmons 7 |
| March 9, 2026 | SOUTHERN CALIFORNIA TROJANS Big 10 Tournament | W 93-74 | 22-8 | A. Johnson 27 | D. Williams 5 | E. Darby 9 |
| March 10, 2026 | @ #12 Michigan Wolverines Big 10 Tournament | W 82-72 | 23-8 | J. Brennan 26 | E. Darby 5 | K. Mason 6 |
| March 11, 2026 | @ #11 Illinois Fighting Illini Big 10 Tournament | L 93-104 | 23-9 | A. Johnson 24 | J. Brennan 5 | K. Mason 9 |
| March 16, 2026 | ST. THOMAS TOMMIES NCAA Tournament | W 107-72 | 24-9 | J. Brennan 24 | A. Johnson 4 | J. Simmons 8 |
| March 18, 2026 | @ #12 Illinois Fighting Illini NCAA Tournament | W 86-74 | 25-9 | J. Brennan 18 | J. Brennan 7 | J. Simmons 11 |
| March 23, 2026 | #20 MISSOURI TIGERS NCAA Tournament | W 94-85 | 26-9 | J. Brennan 37 | A. Johnson 5 | A. Johnson 7 |
| March 25, 2026 | @ #4 Brigham Young Cougars NCAA Tournament | L 65-92 | 26-10 | A. Johnson 14 | J. Brennan 6 | K. Mason 7 |
