| November 14, 2025 | @ #25 Texas Tech Red Raiders | W 93-87 | 1-0 | A. Conway 16 | J. Mannion 12 | M. Felton 6 |
| November 21, 2025 | @ Notre Dame Fighting Irish | W 90-86 | 2-0 | A. Conway 28 | J. Mannion 5 | N. Shannon 13 |
| November 24, 2025 | INDIANA STATE SYCAMORES | W 65-52 | 3-0 | A. Conway 15 | J. Mannion 3 | T. Murray 18 |
| November 28, 2025 | BOSTON COLLEGE EAGLES | W 75-65 | 4-0 | L. Campbell 23 | J. Mannion 6 | T. Murray 8 |
| December 5, 2025 | NORTH DAKOTA ST. BISON | W 85-67 | 5-0 | T. Murray 21 | J. Mannion 8 | T. Murray 15 |
| December 8, 2025 | UC-IRVINE ANTEATERS | W 66-56 | 6-0 | A. Conway 15 | J. Mannion 5 | T. Murray 14 |
| December 12, 2025 | @ Boise State Broncos | W 82-68 | 7-0 | A. Conway 15 | L. Campbell 5 | L. Campbell 7 |
| December 16, 2025 | DREXEL DRAGONS Diamond Head Classic | W 73-45 | 8-0 | L. Campbell 20 | J. Mannion 9 | T. Murray 10 |
| December 17, 2025 | CALIFORNIA GOLDEN BEARS Diamond Head Classic | W 63-62 | 9-0 | A. Webster 13 | J. Mannion 5 | T. Murray 11 |
| December 18, 2025 | YALE BULLDOGS Diamond Head Classic | W 74-70 | 10-0 | J. Mannion 15 | J. Mannion 4 | T. Murray 9 |
| December 19, 2025 | WESTERN KENTUCKY HILLTOPPERS | W 103-96 | 11-0 | A. Conway 24 | J. Mannion 6 | T. Murray 12 |
| December 26, 2025 | @ Southern California Trojans* | W 86-73 | 12-0 | J. Mannion 18 | J. Mannion 5 | T. Murray 14 |
| December 28, 2025 | NEBRASKA CORNHUSKERS* | W 83-77 | 13-0 | J. Mannion 19 | J. Mannion 5 | T. Murray 11 |
| January 2, 2026 | @ Ohio State Buckeyes* | W 77-73 | 14-0 | A. Conway 19 | J. Mannion 3 | T. Murray 14 |
| January 4, 2026 | @ Oregon Ducks* | L 89-92 OT | 14-1 | A. Conway 26 | J. Mannion 8 | L. Campbell 10 |
| January 9, 2026 | @ #12 Minnesota Golden Gophers* | L 71-90 | 14-2 | A. Conway 15 | J. Mannion 4 | T. Murray 8 |
| January 11, 2026 | @ UCLA Bruins* | W 92-84 | 15-2 | A. Conway 19 | L. Campbell 4 | T. Murray 8 |
| January 16, 2026 | PENN STATE NITTANY LIONS* | W 89-73 | 16-2 | A. Conway 23 | J. Mannion 5 | T. Murray 10 |
| January 18, 2026 | @ #18 Illinois Fighting Illini* | W 74-63 | 17-2 | T. Murray 16 | D. James 5 | T. Murray 12 |
| January 23, 2026 | @ Indiana Hoosiers* | L 68-83 | 17-3 | A. Conway 21 | M. Felton 4 | A. Conway 8 |
| January 25, 2026 | #8 MICHIGAN WOLVERINES* | W 96-87 OT | 18-3 | L. Campbell 21 | J. Mannion 6 | T. Murray 13 |
| January 30, 2026 | MARYLAND TERRAPINS* | W 73-51 | 19-3 | A. Conway 13 | J. Mannion 6 | A. Conway 10 |
| February 1, 2026 | #13 WASHINGTON HUSKIES* | W 93-75 | 20-3 | A. Conway 26 | A. Conway 6 | T. Murray 13 |
| February 6, 2026 | @ #4 Purdue Boilermakers* | L 60-83 | 20-4 | T. Murray 16 | J. Mannion 4 | J. Mannion 6 |
| February 8, 2026 | NORTHWESTERN WILDCATS* | W 89-78 | 21-4 | A. Conway 24 | L. Campbell 4 | J. Broussard 8 |
| February 13, 2026 | IOWA HAWKEYES* | W 94-75 | 22-4 | A. Conway 24 | A. Conway 4 | J. Broussard 11 |
| February 15, 2026 | @ Wisconsin Badgers* | L 60-77 | 22-5 | A. Conway 21 | J. Mannion 4 | T. Murray 11 |
| February 20, 2026 | RUTGERS SCARLET KNIGHTS* | W 73-46 | 23-5 | A. Conway 25 | J. Mannion 3 | T. Murray 9 |
| February 22, 2026 | @ Rutgers Scarlet Knights* | W 82-67 | 24-5 | A. Conway 19 | M. Felton 4 | A. Conway 9 |
| February 27, 2026 | OREGON DUCKS* | L 70-74 | 24-6 | T. Murray 15 | J. Mannion 3 | T. Murray 10 |
| March 1, 2026 | OHIO STATE BUCKEYES* | W 77-59 | 25-6 | A. Conway 20 | J. Mannion 5 | A. Conway 8 |
| March 9, 2026 | INDIANA HOOSIERS Big 10 Tournament | W 90-85 | 26-6 | A. Conway 24 | D. James 4 | A. Conway 9 |
| March 10, 2026 | @ #19 Wisconsin Badgers Big 10 Tournament | W 83-71 | 27-6 | A. Conway 18 | J. Mannion 4 | T. Murray 12 |
| March 11, 2026 | @ #5 Purdue Boilermakers Big 10 Tournament | L 71-90 | 27-7 | A. Conway 14 | L. Campbell 4 | T. Murray 13 |
| March 17, 2026 | NJIT HIGHLANDERS NCAA Tournament | W 77-67 | 28-7 | A. Conway 18 | L. Campbell 5 | T. Murray 21 |
| March 19, 2026 | WAKE FOREST DEMON DEACONS NCAA Tournament | L 79-80 OT | 28-8 | T. Murray 20 | J. Mannion 4 | T. Murray 16 |
