| November 14, 2025 | #11 CINCINNATI BEARCATS | W 77-47 | 1-0 | D. Lewis 14 | D. Lewis 4 | C. Trombley 9 |
| November 19, 2025 | RADFORD HIGHLANDERS | W 85-55 | 2-0 | D. Lewis 19 | L. Friend 6 | C. Trombley 6 |
| November 21, 2025 | MIDDLE TENNESSEE BLUE RAIDERS | W 77-58 | 3-0 | D. Lewis 21 | L. Friend 5 | A. Petteway 6 |
| November 24, 2025 | CHARLESTON COUGARS | W 88-66 | 4-0 | L. Friend 24 | C. Trombley 5 | C. Trombley 12 |
| November 28, 2025 | TEXAS-SAN ANTONIO ROADRUNNERS | W 90-74 | 5-0 | C. Trombley 17 | C. Trombley 5 | A. Williams 8 |
| December 5, 2025 | WASHINGTON STATE COUGARS | W 87-72 | 6-0 | C. Trombley 20 | L. Friend 7 | A. Williams 12 |
| December 9, 2025 | LOYOLA (IL) RAMBLERS Cayman Islands Classic | W 72-51 | 7-0 | D. Lewis 16 | D. Lewis 5 | A. Williams 11 |
| December 10, 2025 | @ Kansas State Wildcats Cayman Islands Classic | W 83-72 | 8-0 | C. Trombley 17 | D. Lewis 5 | A. Petteway 12 |
| December 11, 2025 | @ #25 Tennessee Volunteers Cayman Islands Classic | W 62-52 | 9-0 | C. Trombley 14 | D. Lewis 3 | A. Williams 11 |
| December 12, 2025 | SOUTHERN MISSISSIPPI GOLDEN EAGLES | W 88-55 | 10-0 | C. Trombley 16 | D. Lewis 6 | C. Trombley 10 |
| December 20, 2025 | WEST GEORGIA WOLFPACK | W 98-60 | 11-0 | D. Lewis 20 | T. Turner 8 | A. Williams 10 |
| December 26, 2025 | PENN STATE NITTANY LIONS* | W 82-47 | 12-0 | L. Friend 15 | L. Friend 4 | C. Trombley 8 |
| December 28, 2025 | #13 IOWA HAWKEYES* | W 110-98 OT | 13-0 | D. Lewis 24 | D. Lewis 4 | C. Trombley 12 |
| January 2, 2026 | @ #11 Michigan Wolverines* | L 76-99 | 13-1 | L. Friend 17 | D. Lewis 4 | A. Williams 10 |
| January 4, 2026 | @ #2 Purdue Boilermakers* | W 78-71 OT | 14-1 | L. Friend 29 | A. Petteway 5 | C. Trombley 12 |
| January 9, 2026 | #6 MICHIGAN STATE SPARTANS* | W 90-71 | 15-1 | L. Friend 17 | C. Trombley 4 | A. Petteway 9 |
| January 11, 2026 | @ Northwestern Wildcats* | L 58-84 | 15-2 | C. Trombley 17 | J. Wilson 3 | J. Miller 7 |
| January 16, 2026 | @ Rutgers Scarlet Knights* | W 92-73 | 16-2 | D. Lewis 26 | C. Trombley 7 | C. Trombley 9 |
| January 18, 2026 | WISCONSIN BADGERS* | L 71-76 | 16-3 | D. Lewis 20 | C. Trombley 5 | A. Williams 8 |
| January 23, 2026 | @ Ohio State Buckeyes* | W 88-77 | 17-3 | L. Friend 21 | L. Friend 4 | C. Trombley 10 |
| January 25, 2026 | OREGON DUCKS* | W 80-64 | 18-3 | D. Lewis 21 | L. Friend 4 | C. Trombley 8 |
| January 30, 2026 | #17 ILLINOIS FIGHTING ILLINI* | L 69-72 | 18-4 | L. Friend 22 | D. Lewis 4 | C. Trombley 7 |
| February 1, 2026 | @ Nebraska Cornhuskers* | L 69-83 | 18-5 | D. Lewis 20 | D. Lewis 4 | A. Williams 7 |
| February 6, 2026 | @ UCLA Bruins* | L 62-81 | 18-6 | L. Friend 16 | D. Lewis 6 | A. Petteway 6 |
| February 8, 2026 | @ Southern California Trojans* | W 79-61 | 19-6 | T. Turner 16 | C. Trombley 5 | A. Williams 7 |
| February 13, 2026 | #16 WASHINGTON HUSKIES* | W 85-66 | 20-6 | D. Lewis 13 | L. Friend 4 | V. Miner 9 |
| February 15, 2026 | MARYLAND TERRAPINS* | W 86-55 | 21-6 | L. Friend 25 | C. Trombley 5 | A. Williams 8 |
| February 20, 2026 | INDIANA HOOSIERS* | W 72-61 | 22-6 | C. Trombley 19 | D. Lewis 2 | A. Petteway 8 |
| February 22, 2026 | @ Penn State Nittany Lions* | W 83-72 | 23-6 | L. Friend 17 | J. Patterson 3 | A. Petteway 8 |
| February 27, 2026 | @ Iowa Hawkeyes* | L 80-89 | 23-7 | L. Friend 21 | D. Lewis 7 | A. Williams 10 |
| March 1, 2026 | #5 PURDUE BOILERMAKERS* | L 77-93 | 23-8 | D. Lewis 16 | D. Lewis 4 | A. Petteway 7 |
| March 9, 2026 | WASHINGTON HUSKIES Big 10 Tournament | W 82-73 | 24-8 | C. Trombley 21 | L. Friend 8 | A. Williams 10 |
| March 10, 2026 | @ #5 Purdue Boilermakers Big 10 Tournament | L 72-81 | 24-9 | D. Lewis 19 | D. Lewis 4 | A. Williams 10 |
| March 16, 2026 | VIRGINIA CAVALIERS NCAA Tournament | W 91-88 | 25-9 | L. Friend 23 | D. Lewis 5 | L. Friend 8 |
| March 18, 2026 | @ #4 Brigham Young Cougars NCAA Tournament | L 66-76 | 25-10 | A. Williams 17 | L. Friend 5 | A. Williams 7 |
