| November 14, 2025 | VANDERBILT COMMODORES | W 90-74 | 1-0 | J. James 18 | J. James 6 | M. Wheeler 6 |
| November 17, 2025 | SYRACUSE ORANGE | W 80-59 | 2-0 | J. James 28 | J. James 4 | M. Wheeler 18 |
| November 21, 2025 | WESTERN ILLINOIS LEATHERNECKS | W 95-60 | 3-0 | Q. Goree 38 | B. Block 6 | C. Hammond 7 |
| November 24, 2025 | JACKSONVILLE STATE GAMECOCKS | W 81-70 | 4-0 | Q. Goree 19 | J. James 10 | M. Wheeler 16 |
| November 28, 2025 | BALL STATE CARDINALS | W 87-85 OT | 5-0 | J. James 20 | J. James 11 | M. Wheeler 14 |
| December 5, 2025 | ARKANSAS-PINE BLUFF GOLDEN LIONS | W 98-83 | 6-0 | J. James 28 | Q. Goree 6 | Q. Goree 9 |
| December 12, 2025 | NICHOLLS STATE COLONELS | W 96-67 | 7-0 | Q. Goree 22 | Q. Goree 6 | M. Wheeler 13 |
| December 19, 2025 | @ Nevada Wolfpack | L 72-75 | 7-1 | J. James 22 | J. James 4 | M. Wheeler 9 |
| December 23, 2025 | @ UCLA Bruins Empire Classic | L 70-84 | 7-2 | J. James 19 | J. James 5 | M. Wheeler 13 |
| December 26, 2025 | @ Xavier Musketeers* | W 84-77 | 8-2 | B. Block 30 | Q. Goree 3 | B. Block 8 |
| December 28, 2025 | #18 CONNECTICUT HUSKIES* | W 90-74 | 9-2 | Q. Goree 37 | J. James 4 | M. Wheeler 13 |
| January 2, 2026 | @ St. Johns Red Storm* | W 83-75 | 10-2 | Q. Goree 25 | Q. Goree 9 | M. Wheeler 11 |
| January 4, 2026 | DEPAUL BLUE DEMONS* | W 78-66 | 11-2 | J. James 19 | J. James 9 | M. Wheeler 14 |
| January 11, 2026 | PROVIDENCE FRIARS* | W 87-74 | 12-2 | J. James 27 | J. James 5 | M. Wheeler 7 |
| January 13, 2026 | @ Creighton Blue Jays* | L 64-69 | 12-3 | Q. Goree 15 | Q. Goree 6 | M. Wheeler 18 |
| January 20, 2026 | GEORGETOWN HOYAS* | W 105-81 | 13-3 | J. James 33 | J. James 6 | B. Diarra 7 |
| January 23, 2026 | BUTLER BULLDOGS* | W 71-60 | 14-3 | J. James 20 | J. James 5 | M. Wheeler 12 |
| January 27, 2026 | @ Marquette Golden Eagles* | L 76-83 | 14-4 | M. Wheeler 24 | Q. Goree 11 | M. Wheeler 19 |
| January 30, 2026 | @ Villanova Wildcats* | L 77-79 | 14-5 | B. Block 17 | J. James 5 | M. Wheeler 8 |
| February 1, 2026 | @ DePaul Blue Demons* | L 67-82 | 14-6 | J. James 19 | J. James 6 | B. Diarra 6 |
| February 3, 2026 | CREIGHTON BLUE JAYS* | W 76-61 | 15-6 | Q. Goree 24 | Q. Goree 8 | M. Wheeler 19 |
| February 8, 2026 | @ Providence Friars* | L 91-93 OT | 15-7 | M. Wheeler 31 | Q. Goree 6 | M. Wheeler 10 |
| February 13, 2026 | @ #12 Connecticut Huskies* | L 62-77 | 15-8 | M. Wheeler 18 | Q. Goree 4 | M. Wheeler 10 |
| February 15, 2026 | MARQUETTE GOLDEN EAGLES* | W 89-63 | 16-8 | M. Wheeler 22 | Q. Goree 8 | M. Wheeler 13 |
| February 17, 2026 | VILLANOVA WILDCATS* | W 74-69 | 17-8 | J. James 16 | J. James 8 | M. Wheeler 14 |
| February 22, 2026 | @ Georgetown Hoyas* | W 83-76 | 18-8 | Q. Goree 24 | Q. Goree 4 | M. Wheeler 12 |
| February 24, 2026 | @ Butler Bulldogs* | L 72-77 | 18-9 | B. Diarra 17 | Q. Goree 6 | C. Hammond 6 |
| March 1, 2026 | XAVIER MUSKETEERS* | W 111-92 | 19-9 | J. James 30 | J. James 5 | M. Wheeler 17 |
| March 3, 2026 | ST. JOHNS RED STORM* | W 82-47 | 20-9 | J. James 27 | J. James 7 | M. Wheeler 12 |
| March 10, 2026 | MARQUETTE GOLDEN EAGLES Big East Tournament | W 91-72 | 21-9 | Q. Goree 27 | J. James 8 | C. Hammond 9 |
| March 11, 2026 | PROVIDENCE FRIARS Big East Tournament | W 89-84 OT | 22-9 | J. James 33 | Q. Goree 6 | Q. Goree 6 |
| March 12, 2026 | @ St. Johns Red Storm Big East Tournament | W 76-49 | 23-9 | M. Wheeler 18 | J. James 9 | M. Wheeler 17 |
| March 16, 2026 | @ #19 Wichita State Shockers NCAA Tournament | L 76-84 | 23-10 | C. Hammond 20 | Q. Goree 4 | M. Wheeler 12 |
