| November 13, 2025 | NC-CENTRAL EAGLES | W 70-63 | 1-0 | J. Thompson 18 | J. Thompson 5 | J. Thompson 8 |
| November 19, 2025 | BETHUNE-COOKMAN WILDCATS | W 76-55 | 2-0 | J. Thompson 12 | J. Thompson 4 | J. Thompson 14 |
| November 20, 2025 | EAST TENNESSEE STATE BUCCANEERS | W 72-52 | 3-0 | R. Ramsey 15 | R. Ramsey 4 | J. Franklin 9 |
| November 28, 2025 | TEMPLE OWLS | W 89-58 | 4-0 | J. Thompson 18 | R. Ramsey 4 | L. Copeland 11 |
| December 1, 2025 | PENNSYLVANIA QUAKERS | W 81-61 | 5-0 | J. Franklin 17 | J. Thompson 7 | L. Copeland 13 |
| December 5, 2025 | OMAHA MAVERICKS | W 69-58 | 6-0 | J. Thompson 16 | J. Thompson 6 | G. Lewis 10 |
| December 13, 2025 | EASTERN WASHINGTON EAGLES | W 83-59 | 7-0 | R. Ramsey 18 | N. Charles 5 | G. Lewis 7 |
| December 16, 2025 | @ Colorado Buffaloes Diamond Head Classic | W 68-57 | 8-0 | J. Thompson 25 | J. Thompson 4 | J. Franklin 9 |
| December 17, 2025 | @ #15 Michigan State Spartans Diamond Head Classic | L 62-63 | 8-1 | N. Charles 12 | R. Ramsey 4 | J. Franklin 8 |
| December 20, 2025 | WAGNER SEAHAWKS | W 79-64 | 9-1 | J. Thompson 19 | J. Thompson 4 | L. Copeland 7 |
| December 26, 2025 | PITTSBURGH PANTHERS* | W 93-84 | 10-1 | J. Franklin 15 | J. Thompson 6 | J. Franklin 7 |
| December 28, 2025 | @ Notre Dame Fighting Irish* | L 59-77 | 10-2 | J. Franklin 21 | J. Thompson 6 | J. Thompson 7 |
| January 2, 2026 | FLORIDA STATE SEMINOLES* | W 74-62 | 11-2 | J. Franklin 32 | J. Thompson 7 | G. Lewis 12 |
| January 4, 2026 | BOSTON COLLEGE EAGLES* | W 81-58 | 12-2 | L. Copeland 17 | J. Franklin 5 | L. Copeland 7 |
| January 9, 2026 | @ Southern Methodist Mustangs* | L 56-76 | 12-3 | J. Franklin 16 | E. Seek 5 | L. Copeland 6 |
| January 11, 2026 | @ #20 North Carolina Tar Heels* | L 54-70 | 12-4 | E. Seek 16 | J. Franklin 2 | L. Copeland 9 |
| January 16, 2026 | #1 DUKE BLUE DEVILS* | L 63-84 | 12-5 | J. Franklin 16 | G. Lewis 4 | L. Copeland 8 |
| January 18, 2026 | @ Stanford Cardinal* | W 77-66 | 13-5 | J. Thompson 15 | L. Copeland 5 | J. Thompson 9 |
| January 23, 2026 | NC-STATE WOLFPACK* | W 58-51 | 14-5 | J. Thompson 14 | J. Franklin 4 | G. Lewis 9 |
| January 25, 2026 | @ Virginia Cavaliers* | L 77-88 | 14-6 | J. Thompson 19 | J. Thompson 3 | L. Copeland 8 |
| January 30, 2026 | WAKE FOREST DEMON DEACONS* | L 63-71 | 14-7 | R. Ramsey 17 | J. Thompson 6 | J. Thompson 7 |
| February 1, 2026 | LOUISVILLE CARDINALS* | L 58-70 | 14-8 | J. Thompson 14 | R. Ramsey 6 | J. Thompson 7 |
| February 6, 2026 | @ Clemson Tigers* | L 65-74 | 14-9 | R. Ramsey 11 | J. Thompson 6 | J. Franklin 7 |
| February 8, 2026 | GEORGIA TECH YELLOW JACKETS* | W 87-72 | 15-9 | J. Thompson 18 | J. Thompson 6 | L. Copeland 9 |
| February 13, 2026 | @ Miami (FL) Hurricanes* | L 68-78 | 15-10 | J. Thompson 22 | R. Ramsey 2 | G. Lewis 6 |
| February 15, 2026 | VIRGINIA TECH HOKIES* | W 62-60 | 16-10 | J. Franklin 15 | R. Ramsey 4 | J. Franklin 7 |
| February 20, 2026 | @ Syracuse Orange* | L 54-57 | 16-11 | J. Franklin 10 | J. Thompson 2 | G. Lewis 10 |
| February 22, 2026 | @ Georgia Tech Yellow Jackets* | L 71-76 | 16-12 | J. Franklin 16 | R. Ramsey 6 | J. Franklin 8 |
| February 27, 2026 | VIRGINIA CAVALIERS* | L 63-81 | 16-13 | J. Franklin 10 | R. Ramsey 5 | L. Copeland 10 |
| March 1, 2026 | @ Florida State Seminoles* | L 65-77 | 16-14 | N. Charles 14 | J. Thompson 6 | G. Lewis 7 |
| March 8, 2026 | VIRGINIA TECH HOKIES ACC Tournament | L 65-76 | 16-15 | N. Charles 21 | R. Ramsey 5 | J. Franklin 8 |
